Pyridoxine hydrochloride and Sinusitis - a phase IV clinical study of FDA data


We study 1,424 people who have side effects when taking Pyridoxine hydrochloride. Sinusitis is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Gabapentin and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people take Pyridoxine hydrochloride and have Sinusitis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

1,424 people reported to have side effects when taking Pyridoxine hydrochloride.
Among them, 19 people (1.33%) have Sinusitis.

What is Pyridoxine hydrochloride?

Pyridoxine hydrochloride has active ingredients of pyridoxine hydrochloride. Currently, eHealthMe is studying from 1,466 Pyridoxine hydrochloride users.

What is Sinusitis?

Sinusitis (inflammation of sinus) is found to be associated with 3,440 drugs and 2,611 conditions by eHealthMe. Currently, we are studying 143,797 people who have Sinusitis.

Number of Pyridoxine hydrochloride and Sinusitis reports submitted per year:

Could Pyridoxine hydrochloride cause Sinusitis?

Time on Pyridoxine hydrochloride when people have Sinusitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Sinusitis when taking Pyridoxine hydrochloride *:

  • female: 88.89 %
  • male: 11.11 %

Age of people who have Sinusitis when taking Pyridoxine hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 6.25 %
  • 10-19: 0.0 %
  • 20-29: 6.25 %
  • 30-39: 25.0 %
  • 40-49: 6.25 %
  • 50-59: 6.25 %
  • 60+: 50.0 %

Common drugs people take besides Pyridoxine hydrochloride *:

  1. Gabapentin: 8 people, 42.11%
  2. Epinephrine: 7 people, 36.84%
  3. Vitamins: 7 people, 36.84%
  4. Budesonide: 7 people, 36.84%
  5. Vitamin B12: 7 people, 36.84%
  6. Acetaminophen: 6 people, 31.58%
  7. Nystatin: 6 people, 31.58%
  8. Allegra: 6 people, 31.58%
  9. Tramadol: 6 people, 31.58%
  10. Pantoprazole: 5 people, 26.32%

Common side effects people have besides Sinusitis *:

  1. Headache (pain in head): 8 people, 42.11%
  2. Fatigue (feeling of tiredness): 8 people, 42.11%
  3. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 31.58%
  4. Upper Respiratory Tract Infection: 6 people, 31.58%
  5. Asthma: 5 people, 26.32%
  6. Cough: 5 people, 26.32%
  7. The Flu (the flu is caused by an influenza virus): 5 people, 26.32%
  8. Fungal Infection: 5 people, 26.32%
  9. Weakness: 4 people, 21.05%
  10. Gait Disturbance: 4 people, 21.05%

Common conditions people have *:

  1. Immunodeficiency Common Variable: 4 people, 21.05%
  2. Sleep Disorder: 3 people, 15.79%
  3. Muscle Spasms (muscle contraction): 3 people, 15.79%
  4. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 15.79%
  5. Spinal Muscular Atrophy (wasting of spinal muscles): 1 person, 5.26%
  6. Senile Osteoporosis (weak bones with ageing): 1 person, 5.26%
  7. Pancreatic Neuroendocrine Tumor: 1 person, 5.26%
  8. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 5.26%
  9. Metastases To Bone (cancer spreads to bone): 1 person, 5.26%
  10. Insomnia (sleeplessness): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Pyridoxine hydrochloride and have Sinusitis?

Check whether Sinusitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Pyridoxine hydrochloride side effects by duration, gender and age:

Sinusitis treatments and more:

Common drugs associated with Sinusitis:

All the drugs that are associated with Sinusitis:

Common conditions associated with Sinusitis:

All the conditions that are associated with Sinusitis:

How the study uses the data?

The study uses data from the FDA. It is based on pyridoxine hydrochloride (the active ingredients of Pyridoxine hydrochloride) and Pyridoxine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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