Quinine and Small intestinal obstruction - a phase IV clinical study of FDA data


Small intestinal obstruction is found among people who take Quinine, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Quinine and have Small intestinal obstruction. It is created by eHealthMe based on reports of 4,341 people who have side effects when taking Quinine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 05, 2022

4,341 people reported to have side effects when taking Quinine.
Among them, 14 people (0.32%) have Small intestinal obstruction.

What is Quinine?

Quinine has active ingredients of cinchona. It is often used in leg pain. eHealthMe is studying from 4,431 Quinine users for its effectiveness, alternative drugs and more.

What is Small intestinal obstruction?

Small intestinal obstruction (blockage in small intestine) is found to be associated with 1,491 drugs and 902 conditions by eHealthMe.

Number of Quinine and Small intestinal obstruction reports submitted per year:

Could Quinine cause Small intestinal obstruction?

Gender of people who have Small intestinal obstruction when taking Quinine *:

  • female: 42.86 %
  • male: 57.14 %

Age of people who have Small intestinal obstruction when taking Quinine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 7.14 %
  • 50-59: 0.0 %
  • 60+: 78.57 %

Common drugs people take besides Quinine *:

  1. Xanax: 11 people, 78.57%
  2. Miralax: 11 people, 78.57%
  3. Ultram: 11 people, 78.57%
  4. Lisinopril: 10 people, 71.43%
  5. Doxycycline: 10 people, 71.43%
  6. Zometa: 10 people, 71.43%
  7. Mucinex: 10 people, 71.43%
  8. Spironolactone: 9 people, 64.29%
  9. Mirtazapine: 9 people, 64.29%
  10. Buspar: 9 people, 64.29%

Common side effects people have besides Small intestinal obstruction *:

  1. Pain: 12 people, 85.71%
  2. Stress And Anxiety: 12 people, 85.71%
  3. Pain In Extremity: 12 people, 85.71%
  4. Weakness: 12 people, 85.71%
  5. Fall: 12 people, 85.71%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 12 people, 85.71%
  7. Pneumonia: 11 people, 78.57%
  8. Hypoaesthesia (reduced sense of touch or sensation): 11 people, 78.57%
  9. Fainting (loss of consciousness and postural tone): 11 people, 78.57%
  10. Spinal Column Stenosis (narrowing of spinal column): 11 people, 78.57%

Common conditions people have *:

  1. Toothaches (tooth pain): 9 people, 64.29%
  2. Muscle Spasms (muscle contraction): 9 people, 64.29%
  3. Depression: 3 people, 21.43%
  4. Pain: 2 people, 14.29%
  5. Bone Neoplasm Malignant (cancer of bone): 2 people, 14.29%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
  7. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 7.14%
  8. Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
  9. Metastases To Bone (cancer spreads to bone): 1 person, 7.14%
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Quinine and have Small intestinal obstruction?

Check whether Small intestinal obstruction is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Small intestinal obstruction and when was it recovered:

Expand to all the drugs that have ingredients of cinchona:

Alternative drugs to, pros and cons of Quinine:

Common Quinine side effects:

Browse all side effects of Quinine:

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Small intestinal obstruction treatments and more:

COVID vaccines that are related to Small intestinal obstruction:

Common drugs associated with Small intestinal obstruction:

All the drugs that are associated with Small intestinal obstruction:

Common conditions associated with Small intestinal obstruction:

All the conditions that are associated with Small intestinal obstruction:

How the study uses the data?

The study uses data from the FDA. It is based on cinchona (the active ingredients of Quinine) and Quinine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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