Ramipril and Bile duct obstruction - a phase IV clinical study of FDA data


Bile duct obstruction is found among people who take Ramipril, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Ramipril and have Bile duct obstruction. It is created by eHealthMe based on reports of 123,232 people who have side effects when taking Ramipril from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 24, 2023

123,232 people reported to have side effects when taking Ramipril.
Among them, 22 people (0.02%) have Bile duct obstruction.

What is Ramipril?

Ramipril has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 126,267 Ramipril users for its effectiveness, alternative drugs and more.

What is Bile duct obstruction?

Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder) is found to be associated with 1,190 drugs and 583 conditions by eHealthMe.

Number of Ramipril and Bile duct obstruction reports submitted per year:

Could Ramipril cause Bile duct obstruction?

Time on Ramipril when people have Bile duct obstruction *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Gender of people who have Bile duct obstruction when taking Ramipril *:

  • female: 54.55 %
  • male: 45.45 %

Age of people who have Bile duct obstruction when taking Ramipril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 11.11 %
  • 60+: 66.67 %

Common drugs people take besides Ramipril *:

  1. Lantus: 6 people, 27.27%
  2. Hydrochlorothiazide: 5 people, 22.73%
  3. Sandostatin Lar: 5 people, 22.73%
  4. Actos: 4 people, 18.18%
  5. Lexapro: 3 people, 13.64%
  6. Benicar: 3 people, 13.64%
  7. Rebif: 3 people, 13.64%
  8. Celebrex: 2 people, 9.09%
  9. Indocin: 2 people, 9.09%
  10. Effexor: 2 people, 9.09%

Common side effects people have besides Bile duct obstruction *:

  1. Hair Growth Abnormal: 5 people, 22.73%
  2. Thyroid Cancer: 5 people, 22.73%
  3. Hair Loss: 5 people, 22.73%
  4. Hair Disorder: 5 people, 22.73%
  5. Chest Pain: 4 people, 18.18%
  6. Choledocholithiasis (stones in the common bile duct): 3 people, 13.64%
  7. Biopsy Bile Duct Abnormal: 3 people, 13.64%
  8. Pancreatitis Acute (sudden inflammation of pancreas): 3 people, 13.64%
  9. Cerebral Thrombosis (blood clot in brain): 3 people, 13.64%
  10. Rectal Haemorrhage (bleeding from anus): 3 people, 13.64%

Common conditions people have *:

  1. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 5 people, 22.73%
  2. High Blood Cholesterol: 4 people, 18.18%
  3. Depression: 4 people, 18.18%
  4. Diabetes: 3 people, 13.64%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 13.64%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.64%
  7. Sleep Disorder: 2 people, 9.09%
  8. Hypokalemia (low potassium): 2 people, 9.09%
  9. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 9.09%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ramipril and have Bile duct obstruction?

Check whether Bile duct obstruction is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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All the drugs that are associated with Bile duct obstruction:

Common conditions associated with Bile duct obstruction:

All the conditions that are associated with Bile duct obstruction:

How the study uses the data?

The study uses data from the FDA. It is based on ramipril (the active ingredients of Ramipril) and Ramipril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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