Ramipril and Chillblains - a phase IV clinical study of FDA data
Summary:
Chillblains is found among people who take Ramipril, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Ramipril and have Chillblains. It is created by eHealthMe based on reports of 123,232 people who have side effects when taking Ramipril from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
123,232 people reported to have side effects when taking Ramipril.
Among them, 8 people (0.01%) have Chillblains.
What is Ramipril?
Ramipril has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 126,246 Ramipril users for its effectiveness, alternative drugs and more.
What is Chillblains?
Chillblains (small, itchy swellings on the skin that occur as a reaction to cold) is found to be associated with 186 drugs and 95 conditions by eHealthMe.
Number of Ramipril and Chillblains reports submitted per year:

Time on Ramipril when people have Chillblains *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Chillblains when taking Ramipril *:
- female: 100 %
- male: 0.0 %
Age of people who have Chillblains when taking Ramipril *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
Common drugs people take besides Ramipril *:
- Pentoxifylline: 6 people, 75.00%
- Hydroxocobalamin: 6 people, 75.00%
- Ferrous Fumarate: 6 people, 75.00%
- Clopidogrel: 6 people, 75.00%
- Aspirin: 6 people, 75.00%
- Amlodipine: 6 people, 75.00%
- Losartan: 4 people, 50.00%
- Tafinlar: 1 person, 12.50%
- Mekinist: 1 person, 12.50%
- Advil: 1 person, 12.50%
Common side effects people have besides Chillblains *:
- Pain In Extremity: 6 people, 75.00%
- Oedema Peripheral (superficial swelling): 6 people, 75.00%
- Breathing Difficulty: 1 person, 12.50%
- Chest Pain: 1 person, 12.50%
- Cough: 1 person, 12.50%
- Fainting (loss of consciousness and postural tone): 1 person, 12.50%
- Headache (pain in head): 1 person, 12.50%
- Itching: 1 person, 12.50%
- Throat Irritation: 1 person, 12.50%
- Swelling Face: 1 person, 12.50%
Common conditions people have *:
- Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 12.50%
- Headache (pain in head): 1 person, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Ramipril and have Chillblains?
Check whether Chillblains is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Chillblains and when was it recovered:
Expand to all the drugs that have ingredients of ramipril:
Alternative drugs to, pros and cons of Ramipril:
- Ramipril (126,246 reports)
Common Ramipril side effects:
- Breathing difficulty: 8,189 reports
- Fatigue (feeling of tiredness): 7,681 reports
- High blood pressure: 6,811 reports
- Dizziness: 6,630 reports
- Diarrhea: 6,538 reports
- Hypotension (abnormally low blood pressure): 6,084 reports
- Weakness: 5,748 reports
Browse all side effects of Ramipril:
a b c d e f g h i j k l m n o p q r s t u v w x y zChillblains treatments and more:
- Chillblains (327 reports)
COVID vaccines that are related to Chillblains:
- Chillblains in Moderna COVID Vaccine
- Chillblains in Pfizer BioNTech Covid Vaccine
- Chillblains in Johnson and Johnson Covid Vaccine
All the drugs that are associated with Chillblains:
- Chillblains (186 drugs)
All the conditions that are associated with Chillblains:
- Chillblains (95 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ramipril (the active ingredients of Ramipril) and Ramipril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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