Rayos and Osteoarthritis aggravated - a phase IV clinical study of FDA data
Summary:
Osteoarthritis aggravated is reported only by a few people who take Rayos.
The phase IV clinical study analyzes which people take Rayos and have Osteoarthritis aggravated. It is created by eHealthMe based on reports of 559 people who have side effects while taking Rayos from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
559 people reported to have side effects when taking Rayos.
Among them, 4 people (0.72%) have Osteoarthritis aggravated.
What is Rayos?
Rayos has active ingredients of prednisone. It is often used in systemic lupus erythematosus. eHealthMe is studying from 727 Rayos users for its effectiveness, alternative drugs and more.
What is Osteoarthritis aggravated?
Osteoarthritis aggravated (worse joint disease caused by cartilage loss in a joint) is found to be associated with 805 drugs and 316 conditions by eHealthMe.
Number of Rayos and Osteoarthritis aggravated reports submitted per year:

Gender of people who have Osteoarthritis aggravated when taking Rayos *:
- female: 100 %
- male: 0.0 %
Common drugs people take besides Rayos *:
- Humira: 3 people, 75.00%
- Cimzia: 3 people, 75.00%
- Vitamin D: 1 person, 25.00%
- Prilosec: 1 person, 25.00%
- Plaquenil: 1 person, 25.00%
- Orencia: 1 person, 25.00%
- Neurontin: 1 person, 25.00%
- Advil: 1 person, 25.00%
Common side effects people have besides Osteoarthritis aggravated *:
- Joint Effusion (presence of extra fluid in joint covering): 3 people, 75.00%
- Red Blood Cell Sedimentation Rate Increased: 3 people, 75.00%
- Drug Ineffective: 3 people, 75.00%
- Vitamin D Decreased: 3 people, 75.00%
- Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 75.00%
- Pain: 3 people, 75.00%
- Fatigue (feeling of tiredness): 3 people, 75.00%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 75.00%
- Arthritis Reactive (autoimmune condition that develops in response to an infection in another part of the body): 3 people, 75.00%
- Sacroiliitis (an inflammation of the sacroiliac joint): 3 people, 75.00%
Common conditions people have *:
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 25.00%
* Approximation only. Some reports may have incomplete information.
Do you take Rayos and have Osteoarthritis aggravated?
Check whether Osteoarthritis aggravated is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Osteoarthritis aggravated and when was it recovered:
Expand to all the drugs that have ingredients of prednisone:
Alternative drugs to, pros and cons of Rayos:
- Rayos (727 reports)
Osteoarthritis aggravated treatments and more:
- Osteoarthritis aggravated (97 reports)
COVID vaccines that are related to Osteoarthritis aggravated:
- Osteoarthritis aggravated in Moderna COVID Vaccine
- Osteoarthritis aggravated in Pfizer BioNTech Covid Vaccine
- Osteoarthritis aggravated in Johnson and Johnson Covid Vaccine
Common drugs associated with Osteoarthritis aggravated:
- Abilify: 228 reports
- Accupril: 258 reports
- Accutane: 321 reports
- Acetaminophen: 954 reports
- Acetaminophen and hydrocodone bitartrate: 217 reports
- Acetylsalicylic acid: 492 reports
- Actemra: 1,701 reports
- Actos: 381 reports
- Adalat: 136 reports
- Advair diskus 100/50: 482 reports
- Albuterol: 1,067 reports
- Albuterol sulfate: 295 reports
- Alendronate sodium: 3,082 reports
- Alendronic acid: 111 reports
- Aleve: 363 reports
- Allegra: 637 reports
- Allopurinol: 797 reports
- Alprazolam: 842 reports
- Altace: 318 reports
- Ambien: 1,514 reports
- Amitriptyline hydrochloride: 134 reports
- Amlodipine: 1,394 reports
- Amlodipine besylate: 154 reports
- Amoxicillin: 959 reports
- Anastrozole: 115 reports
- Antivert: 147 reports
- Apixaban: 163 reports
- Aredia: 2,235 reports
- Aricept: 105 reports
- Asacol: 244 reports
- Aspirin: 3,760 reports
- Astelin: 111 reports
- Atenolol: 1,300 reports
- Ativan: 917 reports
- Atorvastatin calcium: 188 reports
- Augmentin: 582 reports
- Avandia: 245 reports
- Avelox: 426 reports
- Azithromycin: 278 reports
- Baby aspirin: 155 reports
- Baclofen: 536 reports
- Bactrim: 512 reports
- Bactrim ds: 125 reports
- Benadryl: 761 reports
- Biaxin: 215 reports
- Biotin: 430 reports
- Breo ellipta: 227 reports
- Budesonide: 123 reports
- Buspar: 170 reports
- Calcium: 1,553 reports
- Calcium citrate: 207 reports
- Carvedilol: 398 reports
- Casodex: 253 reports
- Celebrex: 2,879 reports
- Centrum silver: 331 reports
- Cephalexin: 495 reports
- Chantix: 215 reports
- Chlorhexidine gluconate: 465 reports
- Cimzia: 511 reports
- Cipro: 393 reports
- Citalopram hydrobromide: 243 reports
- Claritin: 450 reports
- Clonazepam: 848 reports
- Clopra: 371 reports
- Clotrimazole: 129 reports
- Codeine: 345 reports
- Coenzyme q10: 123 reports
- Colchicine: 124 reports
- Compazine: 123 reports
- Coumadin: 1,469 reports
- Crestor: 980 reports
- Cymbalta: 1,462 reports
- Dexilant: 136 reports
- Diazepam: 570 reports
- Diclofenac sodium: 429 reports
- Dilaudid: 971 reports
- Diovan: 832 reports
- Doxycycline: 554 reports
- Duragesic: 573 reports
- Effexor: 956 reports
- Effexor xr: 230 reports
- Eliquis: 279 reports
- Enbrel: 5,489 reports
- Escitalopram: 195 reports
- Famotidine: 404 reports
- Famvir: 144 reports
- Faslodex: 488 reports
- Fentanyl citrate: 147 reports
- Finasteride: 177 reports
- Fish oil: 876 reports
- Flexeril: 938 reports
- Flomax: 428 reports
- Flonase: 645 reports
- Fluconazole: 513 reports
- Fluorouracil: 169 reports
- Fluoxetine: 460 reports
- Folic acid: 1,060 reports
- Forteo: 669 reports
- Fosamax: 8,826 reports
- Furosemide: 1,423 reports
- Gabapentin: 2,141 reports
- Gemzar: 233 reports
- Gentamicin: 105 reports
- Genvoya: 135 reports
- Humira: 8,489 reports
- Hydrochlorothiazide: 1,734 reports
- Hydrocodone bitartrate and acetaminophen: 332 reports
- Hydroxychloroquine sulfate: 782 reports
- Ibu: 1,750 reports
- Ibuprofen: 1,742 reports
- Inderal: 123 reports
- Keflex: 537 reports
- Kenalog: 149 reports
- Keppra: 195 reports
- Klor-con: 417 reports
- Lactulose: 275 reports
- Lansoprazole: 315 reports
- Lantus: 611 reports
- Lasix: 1,869 reports
- Lescol: 101 reports
- Letrozole: 159 reports
- Levaquin: 1,165 reports
- Levothyroxine sodium: 692 reports
- Levoxyl: 292 reports
- Lexapro: 856 reports
- Lidocaine: 241 reports
- Lipitor: 2,179 reports
- Lisinopril: 2,276 reports
- Loratadine: 288 reports
- Lorazepam: 1,066 reports
- Losartan potassium: 268 reports
- Lovenox: 530 reports
- Lupron: 349 reports
- Lyrica: 1,730 reports
- Magnesium: 924 reports
- Maxzide: 187 reports
- Megestrol acetate: 161 reports
- Melatonin: 166 reports
- Meloxicam: 750 reports
- Metformin: 1,928 reports
- Metformin hydrochloride: 237 reports
- Methotrexate: 6,509 reports
- Methylprednisolone: 225 reports
- Metoprolol succinate: 258 reports
- Metoprolol tartrate: 488 reports
- Metronidazole: 391 reports
- Micardis: 255 reports
- Milk of magnesia: 190 reports
- Mirtazapine: 324 reports
- Ms contin: 406 reports
- Multivitamin: 512 reports
- Nabumetone: 158 reports
- Naprosyn: 315 reports
- Navelbine: 251 reports
- Neupogen: 263 reports
- Nexium: 2,199 reports
- Niaspan: 125 reports
- Nitroglycerin: 571 reports
- Nolvadex: 116 reports
- Norvasc: 1,074 reports
- Nuvaring: 103 reports
- Omeprazole: 2,070 reports
- Orencia: 2,219 reports
- Otezla: 324 reports
- Oxycodone: 1,075 reports
- Pantoprazole sodium: 406 reports
- Paracetamol: 430 reports
- Paxil: 762 reports
- Percocet: 1,384 reports
- Phenergan: 535 reports
- Plaquenil: 2,269 reports
- Plavix: 857 reports
- Pradaxa: 106 reports
- Pravastatin sodium: 162 reports
- Prednisolone: 547 reports
- Prednisone: 5,766 reports
- Pregabalin: 395 reports
- Premarin: 1,314 reports
- Prilosec: 1,836 reports
- Prinivil: 279 reports
- Proair hfa: 195 reports
- Probiotic: 121 reports
- Prolia: 800 reports
- Propofol: 126 reports
- Protonix: 1,494 reports
- Provigil: 273 reports
- Prozac: 699 reports
- Ramipril: 618 reports
- Ranitidine: 600 reports
- Rebif: 248 reports
- Remeron: 244 reports
- Remicade: 1,470 reports
- Restasis: 213 reports
- Restoril: 331 reports
- Risperdal: 161 reports
- Rituxan: 1,064 reports
- Robaxin: 182 reports
- Rocephin: 208 reports
- Rosuvastatin calcium: 288 reports
- Sandostatin: 548 reports
- Sandostatin lar: 445 reports
- Senna: 259 reports
- Seroquel: 528 reports
- Sertraline: 526 reports
- Sertraline hydrochloride: 159 reports
- Simvastatin: 1,514 reports
- Singulair: 969 reports
- Soma: 339 reports
- Spiriva: 758 reports
- Spironolactone: 458 reports
- Stelara: 517 reports
- Stribild: 110 reports
- Symbicort: 590 reports
- Synthroid: 2,905 reports
- Tamoxifen citrate: 611 reports
- Tamsulosin: 222 reports
- Taxol: 305 reports
- Tecfidera: 144 reports
- Tenormin: 198 reports
- Topiramate: 163 reports
- Toradol: 247 reports
- Tramadol: 1,376 reports
- Tramadol hydrochloride: 184 reports
- Trazodone hydrochloride: 367 reports
- Triamcinolone acetonide: 108 reports
- Trileptal: 128 reports
- Tylenol: 2,654 reports
- Vagifem: 172 reports
- Vasotec: 216 reports
- Viagra: 228 reports
- Vitamin b12: 872 reports
- Vitamin b6: 116 reports
- Vitamin c: 508 reports
- Vitamin d: 2,088 reports
- Vitamin d3: 829 reports
- Vitamin e: 379 reports
- Vitamins: 2,193 reports
- Warfarin sodium: 531 reports
- Wellbutrin: 856 reports
- Xanax: 1,371 reports
- Xarelto: 319 reports
- Xeljanz: 2,101 reports
- Xeloda: 439 reports
- Xyrem: 393 reports
- Zaroxolyn: 123 reports
- Zestril: 369 reports
- Zetia: 353 reports
- Zocor: 1,047 reports
- Zoledronic acid: 102 reports
- Zoloft: 1,155 reports
- Zolpidem tartrate: 109 reports
- Zyrtec: 775 reports
All the drugs that are associated with Osteoarthritis aggravated:
- Osteoarthritis aggravated (805 drugs)
Common conditions associated with Osteoarthritis aggravated:
- Acid reflux: 1,506 reports
- Ankylosing spondylitis: 819 reports
- Anticoagulant therapy: 286 reports
- Anxiety and stress: 991 reports
- Anxiolytic therapy: 1,131 reports
- Apprehension: 991 reports
- Arthritis: 1,290 reports
- Asthma: 956 reports
- Atrial fibrillation: 339 reports
- Auricular fibrillation: 339 reports
- Back pain: 515 reports
- Back pain aggravated: 515 reports
- Bhp: 117 reports
- Bladder infection: 148 reports
- Breast cancer: 804 reports
- Breast cancer metastatic: 358 reports
- Copd: 310 reports
- Crohn's disease: 1,159 reports
- Depression: 1,688 reports
- Dyslipidemia: 2,297 reports
- Dyspnoea exacerbated: 142 reports
- Fibromyalgia: 460 reports
- Gastric disorder: 300 reports
- Gastric ulcer: 146 reports
- Gastritis aggravated: 131 reports
- Gastroesophageal reflux disease: 1,645 reports
- Gerd: 1,506 reports
- High blood cholesterol: 2,214 reports
- High blood cholesterol and triglycerides: 2,297 reports
- High blood pressure: 3,930 reports
- Hyperlipidaemia: 322 reports
- Hyperlipidemia: 2,214 reports
- Inflammation: 203 reports
- Insomnia: 527 reports
- Ldl/hdl ratio increased: 2,433 reports
- Lipoprotein test: 2,214 reports
- Menopause: 189 reports
- Metastases to bone: 728 reports
- Ms: 1,683 reports
- Multiple myeloma: 1,015 reports
- Muscle spasms: 403 reports
- Neoplasm malignant: 210 reports
- Osteopenia: 3,144 reports
- Osteoporosis: 7,831 reports
- Osteoporosis post-menopausal: 343 reports
- Pain: 3,547 reports
- Parkinson's disease: 203 reports
- Pimples: 194 reports
- Plasmacytoma of bone: 1,015 reports
- Pneumonia: 105 reports
- Polyarthritis: 141 reports
- Preventive health care: 532 reports
- Prostate cancer: 259 reports
- Psoriasis: 1,368 reports
- Psoriatic arthropathy: 1,829 reports
- Ra: 9,564 reports
- Relapsing-remitting multiple sclerosis: 165 reports
- Restless leg syndrome: 216 reports
- Rheumatoid arthritis: 10,391 reports
- Sleep disorder: 760 reports
- Sleep - too much: 800 reports
- Spondylarthropathy: 819 reports
- Stress and anxiety: 991 reports
- Stroke: 194 reports
- Systemic lupus erythematosus: 255 reports
- Tachycardia: 110 reports
- Thin bones: 7,484 reports
All the conditions that are associated with Osteoarthritis aggravated:
- Osteoarthritis aggravated (316 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on prednisone (the active ingredients of Rayos) and Rayos (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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