Reclast and Corneal abrasion - a phase IV clinical study of FDA data


Corneal abrasion is reported only by a few people who take Reclast.

The phase IV clinical study analyzes which people take Reclast and have Corneal abrasion. It is created by eHealthMe based on reports of 14,324 people who have side effects while taking Reclast from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 26, 2023

14,324 people reported to have side effects when taking Reclast.
Among them, 3 people (0.02%) have Corneal abrasion.

What is Reclast?

Reclast has active ingredients of zoledronic acid. It is often used in osteoporosis. eHealthMe is studying from 14,634 Reclast users for its effectiveness, alternative drugs and more.

What is Corneal abrasion?

Corneal abrasion (loss of the surface of cornea) is found to be associated with 731 drugs and 349 conditions by eHealthMe.

Number of Reclast and Corneal abrasion reports submitted per year:

Could Reclast cause Corneal abrasion?

Time on Reclast when people have Corneal abrasion *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Corneal abrasion when taking Reclast *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Corneal abrasion when taking Reclast *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 50 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 50 %

Common drugs people take besides Reclast *:

  1. Valium: 1 person, 33.33%
  2. Trileptal: 1 person, 33.33%
  3. Rufinamide: 1 person, 33.33%
  4. Remicade: 1 person, 33.33%
  5. Prilosec: 1 person, 33.33%
  6. Nexium: 1 person, 33.33%
  7. Methotrexate: 1 person, 33.33%
  8. Loestrin Fe 1/20: 1 person, 33.33%
  9. Keppra: 1 person, 33.33%
  10. Flexeril: 1 person, 33.33%

Common side effects people have besides Corneal abrasion *:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 66.67%
  2. Influenza Like Illness: 2 people, 66.67%
  3. Swelling Face: 1 person, 33.33%
  4. Eye Disorder: 1 person, 33.33%
  5. Abnormal Behavior: 1 person, 33.33%
  6. Aggression: 1 person, 33.33%
  7. Agitation (state of anxiety or nervous excitement): 1 person, 33.33%
  8. Cataract (clouding of the lens inside the eye): 1 person, 33.33%
  9. Crying: 1 person, 33.33%
  10. Headache (pain in head): 1 person, 33.33%

Common conditions people have *:

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 33.33%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 33.33%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 33.33%
  4. Menstruation Irregular: 1 person, 33.33%
  5. Dysmenorrhea (painful menstruation): 1 person, 33.33%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Reclast and have Corneal abrasion?

Check whether Corneal abrasion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Corneal abrasion and when was it recovered:

Expand to all the drugs that have ingredients of zoledronic acid:

Alternative drugs to, pros and cons of Reclast:

Common Reclast side effects:

Browse all side effects of Reclast:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Corneal abrasion treatments and more:

COVID vaccines that are related to Corneal abrasion:

Common drugs associated with Corneal abrasion:

All the drugs that are associated with Corneal abrasion:

Common conditions associated with Corneal abrasion:

All the conditions that are associated with Corneal abrasion:

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Reclast) and Reclast (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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