Reglan and Extrapyramidal disorder - a phase IV clinical study of FDA data

Summary:

We study 27,946 people who have side effects when taking Reglan. Extrapyramidal disorder is found, especially among people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Metoclopramide and have Abdominal distension.

The phase IV clinical study analyzes which people take Reglan and have Extrapyramidal disorder. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 26, 2023

27,946 people reported to have side effects when taking Reglan.
Among them, 4,988 people (17.85%) have Extrapyramidal disorder.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is used in gastroparesis. Currently, eHealthMe is studying from 29,065 Reglan users.

What is Extrapyramidal disorder?

Extrapyramidal disorder (involuntary muscle spasms in the face and neck) is found to be associated with 1,524 drugs and 939 conditions by eHealthMe. Currently, we are studying 29,787 people who have Extrapyramidal disorder.

Number of Reglan and Extrapyramidal disorder reports submitted per year:

Could Reglan cause Extrapyramidal disorder?

* Approximation only. Some reports may have incomplete information.

Do you take Reglan and have Extrapyramidal disorder?

Check whether Extrapyramidal disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Reglan side effects by duration, gender and age:

Reglan side effects (29,065 reports)

Extrapyramidal disorder treatments and more:

Extrapyramidal disorder (29,787 reports)

Common drugs associated with Extrapyramidal disorder:

Metoclopramide: 14,572 reports
Clopra: 14,529 reports
Reglan: 4,988 reports
Risperdal: 2,455 reports
Risperidone: 1,824 reports
Abilify: 1,248 reports
Metoclopramide hydrochloride: 1,107 reports
Olanzapine: 1,003 reports
Haloperidol: 845 reports
Aripiprazole: 739 reports

All the drugs that are associated with Extrapyramidal disorder:

Extrapyramidal disorder (1,524 drugs)

Common conditions associated with Extrapyramidal disorder:

Indigestion: 2,792 reports
Schizophrenia: 1,935 reports
Bipolar disorder: 1,148 reports
Depression: 1,128 reports
Attention deficit hyperactivity disorder: 526 reports
Schizoaffective disorder: 415 reports

All the conditions that are associated with Extrapyramidal disorder:

Extrapyramidal disorder (939 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Reglan) and Reglan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.