Requip and Diplopia - a phase IV clinical study of FDA data
Summary:
Diplopia is found among people who take Requip, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Requip and have Diplopia. It is created by eHealthMe based on reports of 21,035 people who have side effects when taking Requip from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
21,035 people reported to have side effects when taking Requip.
Among them, 65 people (0.31%) have Diplopia.
What is Requip?
Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,093 Requip users for its effectiveness, alternative drugs and more.
What is Diplopia?
Diplopia (double vision) is found to be associated with 2,410 drugs and 1,846 conditions by eHealthMe.
Number of Requip and Diplopia reports submitted per year:

Time on Requip when people have Diplopia *:
- < 1 month: 50 %
- 1 - 6 months: 25 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 25 %
- 10+ years: 0.0 %
Gender of people who have Diplopia when taking Requip *:
- female: 56.45 %
- male: 43.55 %
Age of people who have Diplopia when taking Requip *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 2.17 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 13.04 %
- 50-59: 34.78 %
- 60+: 50.0 %
Common drugs people take besides Requip *:
- Ambien: 10 people, 15.38%
- Sinemet: 9 people, 13.85%
- Lipitor: 8 people, 12.31%
- Protonix: 8 people, 12.31%
- Klonopin: 8 people, 12.31%
- Aspirin: 7 people, 10.77%
- Clonazepam: 7 people, 10.77%
- Zoloft: 6 people, 9.23%
- Cymbalta: 6 people, 9.23%
- Crestor: 6 people, 9.23%
Common side effects people have besides Diplopia *:
- Vision Blurred: 20 people, 30.77%
- Dizziness: 15 people, 23.08%
- Drowsiness: 12 people, 18.46%
- Fall: 10 people, 15.38%
- Headache (pain in head): 10 people, 15.38%
- Insomnia (sleeplessness): 8 people, 12.31%
- Fatigue (feeling of tiredness): 8 people, 12.31%
- Hypotension (abnormally low blood pressure): 7 people, 10.77%
- Muscle Spasms (muscle contraction): 7 people, 10.77%
- Nausea (feeling of having an urge to vomit): 7 people, 10.77%
Common conditions people have *:
- Back Pain: 5 people, 7.69%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 7.69%
- Nerve Block (the interruption of signals travelling along a nerve): 4 people, 6.15%
- Eyelid Twitch (spontaneous and uncontrolled spasms of the muscles): 4 people, 6.15%
- Dry Eyes (lack of adequate tears): 4 people, 6.15%
- Rosacea (a skin condition that causes facial redness): 4 people, 6.15%
- High Blood Pressure: 4 people, 6.15%
- Skin Wrinkling (wrinkle on skin): 4 people, 6.15%
- Anaesthesia: 4 people, 6.15%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 4.62%
* Approximation only. Some reports may have incomplete information.
Do you take Requip and have Diplopia?
Check whether Diplopia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Related studies
How severe was Diplopia and when was it recovered:
Expand to all the drugs that have ingredients of ropinirole hydrochloride:
Alternative drugs to, pros and cons of Requip:
- Requip (22,093 reports)
Common Requip side effects:
- Drug ineffective: 1,870 reports
- Fatigue (feeling of tiredness): 1,331 reports
- Drowsiness: 1,164 reports
- Dizziness: 1,134 reports
- Pain: 1,033 reports
Browse all side effects of Requip:
a b c d e f g h i j k l m n o p q r s t u v w x y zDiplopia treatments and more:
- Diplopia (28,571 reports)
COVID vaccines that are related to Diplopia:
- Diplopia in Moderna COVID Vaccine
- Diplopia in Pfizer BioNTech Covid Vaccine
- Diplopia in Johnson and Johnson Covid Vaccine
Common drugs associated with Diplopia:
- Aspirin: 1,327 reports
- Prednisone: 1,206 reports
- Lyrica: 1,196 reports
- Gabapentin: 920 reports
- Tysabri: 919 reports
- Gilenya: 873 reports
- Avonex: 766 reports
- Synthroid: 752 reports
- Methotrexate: 745 reports
- Omeprazole: 693 reports
All the drugs that are associated with Diplopia:
- Diplopia (2,410 drugs)
Common conditions associated with Diplopia:
- Multiple sclerosis: 3,314 reports
- High blood pressure: 1,169 reports
- Pain: 983 reports
- Depression: 964 reports
- Rheumatoid arthritis: 887 reports
- Epilepsy: 740 reports
All the conditions that are associated with Diplopia:
- Diplopia (1,846 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip) and Requip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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