Requip and Spinal compression fracture - a phase IV clinical study of FDA data

Summary:

Spinal compression fracture is found among people who take Requip, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Requip and have Spinal compression fracture. It is created by eHealthMe based on reports of 21,035 people who have side effects when taking Requip from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 29, 2022

21,035 people reported to have side effects when taking Requip.
Among them, 29 people (0.14%) have Spinal compression fracture.


What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,080 Requip users for its effectiveness, alternative drugs and more.

What is Spinal compression fracture?

Spinal compression fracture (fracture due to spinal compression on bone) is found to be associated with 1,455 drugs and 784 conditions by eHealthMe.

Number of Requip and Spinal compression fracture reports submitted per year:

Could Requip cause Spinal compression fracture?

Time on Requip when people have Spinal compression fracture *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Spinal compression fracture when taking Requip *:

  • female: 78.57 %
  • male: 21.43 %

Age of people who have Spinal compression fracture when taking Requip *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.7 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 3.7 %
  • 50-59: 14.81 %
  • 60+: 77.78 %

Common drugs people take besides Requip *:

  1. Lasix: 10 people, 34.48%
  2. Nexium: 9 people, 31.03%
  3. Zometa: 5 people, 17.24%
  4. Altace: 5 people, 17.24%
  5. Faslodex: 5 people, 17.24%
  6. Flonase: 5 people, 17.24%
  7. Compazine: 5 people, 17.24%
  8. Neurontin: 5 people, 17.24%
  9. Aromasin: 5 people, 17.24%
  10. Aredia: 5 people, 17.24%

Common side effects people have besides Spinal compression fracture *:

  1. Back Pain: 9 people, 31.03%
  2. Cardiac Failure Congestive: 7 people, 24.14%
  3. Fall: 7 people, 24.14%
  4. Anaemia (lack of blood): 7 people, 24.14%
  5. Weakness: 6 people, 20.69%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 20.69%
  7. Brachial Plexopathy (pain, decreased movement, or decreased sensation in the arm and shoulder due to a nerve problem): 5 people, 17.24%
  8. Breast Cancer Metastatic: 5 people, 17.24%
  9. Nausea (feeling of having an urge to vomit): 5 people, 17.24%
  10. Myositis (inflammation of the muscles): 5 people, 17.24%

Common conditions people have *:

  1. Osteoporosis (bones weak and more likely to break): 7 people, 24.14%
  2. Breast Cancer Metastatic: 5 people, 17.24%
  3. Constipation: 4 people, 13.79%
  4. Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 10.34%
  5. Pain: 3 people, 10.34%
  6. Nausea (feeling of having an urge to vomit): 2 people, 6.90%
  7. Weight Decreased: 2 people, 6.90%
  8. Insomnia (sleeplessness): 2 people, 6.90%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.90%
  10. Neuropathy Peripheral (surface nerve damage): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and have Spinal compression fracture?

Check whether Spinal compression fracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Spinal compression fracture and when was it recovered:

Expand to all the drugs that have ingredients of ropinirole hydrochloride:

Alternative drugs to, pros and cons of Requip:

Common Requip side effects:

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Spinal compression fracture treatments and more:

COVID vaccines that are related to Spinal compression fracture:

Common drugs associated with Spinal compression fracture:

All the drugs that are associated with Spinal compression fracture:

Common conditions associated with Spinal compression fracture:

All the conditions that are associated with Spinal compression fracture:

How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip) and Requip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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