Will you have Application site pain with Restasis - from FDA reports


Application site pain is found among people who take Restasis, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Nexium, and have Birth control. This study is created by eHealthMe based on reports of 19,712 people who have side effects when taking Restasis from FDA, and is updated regularly.

What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on cyclosporine (the active ingredients of Restasis) and Restasis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Synonyms of Application site pain are also considered in the study.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. (latest outcomes from Restasis 20,069 users)

What is Application site pain?

Application site pain has been reported by people with actinic keratosis, pain, quit smoking, migraine, attention deficit hyperactivity disorder (latest reports from 14,059 Application site pain patients).

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 26, 2019

19,712 people reported to have side effects when taking Restasis.
Among them, 48 people (0.24%) have Application site pain

Number of reports submitted per year:

Could Restasis cause Application site pain?

Time on Restasis when people have Application site pain *:

  • < 1 month: 40 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Application site pain when taking Restasis *:

  • female: 87.5 %
  • male: 12.5 %

Age of people who have Application site pain when taking Restasis *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.33 %
  • 40-49: 23.33 %
  • 50-59: 26.67 %
  • 60+: 46.67 %

Top conditions involved for these people *:

  1. Birth Control: 3 people, 6.25%
  2. Supplementation Therapy: 2 people, 4.17%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.17%
  4. Wound: 1 person, 2.08%
  5. Incontinence (lack of moderation or self-control): 1 person, 2.08%
  6. Asthma: 1 person, 2.08%
  7. Attention Deficit Hyperactivity Disorder: 1 person, 2.08%
  8. Breakthrough Pain: 1 person, 2.08%
  9. Breast Cancer: 1 person, 2.08%
  10. Dizziness: 1 person, 2.08%

Top co-used drugs for these people *:

  1. Calcium: 3 people, 6.25%
  2. Nexium: 3 people, 6.25%
  3. Lyrica: 2 people, 4.17%
  4. Cymbalta: 2 people, 4.17%
  5. Vitamin D3: 2 people, 4.17%
  6. Crestor: 2 people, 4.17%
  7. Biotin: 2 people, 4.17%
  8. Synthroid: 2 people, 4.17%
  9. Oxytrol For Women: 2 people, 4.17%
  10. Singulair: 2 people, 4.17%

Top other side effects for these people *:

  1. Application Site Erythema (redness of the skin at application site): 9 people, 18.75%
  2. Application Site Swelling: 4 people, 8.33%
  3. Eye Swelling: 4 people, 8.33%
  4. Application Site Pruritus (application site severe itching of the skin): 4 people, 8.33%
  5. Application Site Reaction: 4 people, 8.33%
  6. Lacrimation Increased: 3 people, 6.25%
  7. Eye Irritation: 3 people, 6.25%
  8. Eye Pain: 3 people, 6.25%
  9. Paraesthesia Oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect): 3 people, 6.25%
  10. Dizziness: 2 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you have Application site pain while taking Restasis?

You are not alone, use our "Ginger Health" app to:

  • connect with people like you who take Restasis and have Application site pain
  • use your healthcare experience to help people like you, and be rewarded

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Browse side effects by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Restasis
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What would happen?

Predict new side effects and undetected conditions when you take Restasis and have Application site pain

FDA reports used in this study

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