Restoril and Sciatica - a phase IV clinical study of FDA data


Sciatica is found among people who take Restoril, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Restoril and have Sciatica. It is created by eHealthMe based on reports of 11,981 people who have side effects when taking Restoril from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

11,981 people reported to have side effects when taking Restoril.
Among them, 62 people (0.52%) have Sciatica.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 12,602 Restoril users for its effectiveness, alternative drugs and more.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,883 drugs and 1,281 conditions by eHealthMe.

Number of Restoril and Sciatica reports submitted per year:

Could Restoril cause Sciatica?

Gender of people who have Sciatica when taking Restoril *:

  • female: 54.1 %
  • male: 45.9 %

Age of people who have Sciatica when taking Restoril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 5.66 %
  • 40-49: 22.64 %
  • 50-59: 9.43 %
  • 60+: 62.26 %

Common drugs people take besides Restoril *:

  1. Coumadin: 43 people, 69.35%
  2. Zometa: 42 people, 67.74%
  3. Aredia: 42 people, 67.74%
  4. Oxycontin: 34 people, 54.84%
  5. Ambien: 32 people, 51.61%
  6. Celebrex: 26 people, 41.94%
  7. Neurontin: 25 people, 40.32%
  8. Lovenox: 25 people, 40.32%
  9. Prozac: 22 people, 35.48%
  10. Mycelex: 21 people, 33.87%

Common side effects people have besides Sciatica *:

  1. Stress And Anxiety: 47 people, 75.81%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 37 people, 59.68%
  3. High Blood Pressure: 36 people, 58.06%
  4. Emotional Distress: 35 people, 56.45%
  5. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 35 people, 56.45%
  6. Osteonecrosis Of Jaw (death of bone of jaw): 34 people, 54.84%
  7. Bone Disorder: 34 people, 54.84%
  8. Pain: 34 people, 54.84%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 33 people, 53.23%
  10. Deformity (disfigurement): 31 people, 50.00%

Common conditions people have *:

  1. Hot Flush (sudden feelings of heat): 11 people, 17.74%
  2. Breast Cancer: 11 people, 17.74%
  3. Pain: 10 people, 16.13%
  4. Prostate Cancer Metastatic: 8 people, 12.90%
  5. High Blood Pressure: 5 people, 8.06%
  6. Chest Pain: 4 people, 6.45%
  7. Back Pain: 3 people, 4.84%
  8. Cardiac Valve Disease (heart valve disease): 3 people, 4.84%
  9. Heart Rate Increased: 3 people, 4.84%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.84%

* Approximation only. Some reports may have incomplete information.

Do you take Restoril and have Sciatica?

Check whether Sciatica is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Restoril:

Sciatica treatments and more:

COVID vaccines that are related to Sciatica:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of temazepam:

Common drugs associated with Sciatica:

All the drugs that are associated with Sciatica:

Common conditions associated with Sciatica:

All the conditions that are associated with Sciatica:

How the study uses the data?

The study uses data from the FDA. It is based on temazepam (the active ingredients of Restoril) and Restoril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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