Roxicet and Fibula fracture - a phase IV clinical study of FDA data


Fibula fracture is found among people who take Roxicet, especially for people who are female, 50-59 old.

The phase IV clinical study analyzes which people take Roxicet and have Fibula fracture. It is created by eHealthMe based on reports of 2,089 people who have side effects when taking Roxicet from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 26, 2022

2,089 people reported to have side effects when taking Roxicet.
Among them, 8 people (0.38%) have Fibula fracture.

What is Roxicet?

Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,196 Roxicet users for its effectiveness, alternative drugs and more.

What is Fibula fracture?

Fibula fracture is found to be associated with 962 drugs and 540 conditions by eHealthMe.

Number of Roxicet and Fibula fracture reports submitted per year:

Could Roxicet cause Fibula fracture?

Gender of people who have Fibula fracture when taking Roxicet *:

  • female: 87.5 %
  • male: 12.5 %

Age of people who have Fibula fracture when taking Roxicet *:

  • 0-1: 12.5 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 87.5 %
  • 60+: 0.0 %

Common drugs people take besides Roxicet *:

  1. Oxycontin: 8 people, 100.00%
  2. Zometa: 7 people, 87.50%
  3. Lexapro: 7 people, 87.50%
  4. Aredia: 7 people, 87.50%
  5. Aromasin: 7 people, 87.50%
  6. Celebrex: 7 people, 87.50%
  7. Combivent: 7 people, 87.50%
  8. Faslodex: 7 people, 87.50%
  9. Femara: 7 people, 87.50%
  10. Flonase: 7 people, 87.50%

Common side effects people have besides Fibula fracture *:

  1. Stress And Anxiety: 8 people, 100.00%
  2. Emotional Distress: 8 people, 100.00%
  3. Infection: 7 people, 87.50%
  4. Fluid Overload (too much fluid in the blood): 7 people, 87.50%
  5. Gallstones (stone formation by bile component): 7 people, 87.50%
  6. General Physical Health Deterioration (weak health status): 7 people, 87.50%
  7. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 7 people, 87.50%
  8. High Blood Pressure: 7 people, 87.50%
  9. Ileal Stenosis (obstruction in the ileal): 7 people, 87.50%
  10. Impaired Healing: 7 people, 87.50%

Common conditions people have *:

  1. Traumatic Injury Of The Bladder And Urethra: 7 people, 87.50%
  2. Metastases To Bone (cancer spreads to bone): 6 people, 75.00%
  3. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 1 person, 12.50%
  4. Metastases To Pelvis (cancer spreads to pelvis): 1 person, 12.50%
  5. Clavicle Fracture: 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicet and have Fibula fracture?

Check whether Fibula fracture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Fibula fracture and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; oxycodone hydrochloride:

Alternative drugs to, pros and cons of Roxicet:

Common Roxicet side effects:

Browse all side effects of Roxicet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Fibula fracture treatments and more:

COVID vaccines that are related to Fibula fracture:

Common drugs associated with Fibula fracture:

All the drugs that are associated with Fibula fracture:

Common conditions associated with Fibula fracture:

All the conditions that are associated with Fibula fracture:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride (the active ingredients of Roxicet) and Roxicet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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