Senna and Breath odor - a phase IV clinical study of FDA data

Summary:

We study 34,731 people who have side effects when taking Senna. Breath odor is found, especially among people who are female, 60+ old, also take Zometa and have Metastases to bone.

The phase IV clinical study analyzes which people take Senna and have Breath odor. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 13, 2023

34,731 people reported to have side effects when taking Senna.
Among them, 34 people (0.1%) have Breath odor.

What is Senna?

Senna has active ingredients of senna. It is used in constipation. Currently, eHealthMe is studying from 34,972 Senna users.

What is Breath odor?

Breath odor is found to be associated with 1,295 drugs and 753 conditions by eHealthMe. Currently, we are studying 3,717 people who have Breath odor.

Number of Senna and Breath odor reports submitted per year:

Gender of people who have Breath odor when taking Senna *:

female: 94.12 %
male: 5.88 %

Age of people who have Breath odor when taking Senna *:

Common drugs people take besides Senna *:

Common side effects people have besides Breath odor *:

Pain: 34 people, 100.00%
Bone Disorder: 32 people, 94.12%
Weakness: 31 people, 91.18%
Osteomyelitis (infection of bone): 31 people, 91.18%
Osteonecrosis Of Jaw (death of bone of jaw): 31 people, 91.18%
Breathing Difficulty: 29 people, 85.29%
Insomnia (sleeplessness): 27 people, 79.41%
Headache (pain in head): 27 people, 79.41%
Weight Decreased: 25 people, 73.53%
Anaemia (lack of blood): 24 people, 70.59%

Common conditions people have *:

Stress And Anxiety: 17 people, 50.00%
Metastases To Bone (cancer spreads to bone): 17 people, 50.00%
Respiratory Tract Infection: 8 people, 23.53%
Renal Cell Carcinoma (a kidney cancer): 8 people, 23.53%
Psychotic Disorder: 8 people, 23.53%
Pneumonia: 8 people, 23.53%
Oedema (fluid collection in tissue): 8 people, 23.53%
Fever: 8 people, 23.53%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 8 people, 23.53%
Breathing Difficulty: 8 people, 23.53%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and have Breath odor?

Check whether Breath odor is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Senna side effects by duration, gender and age:

Senna side effects (34,972 reports)

Breath odor treatments and more:

Breath odor (3,717 reports)

Common drugs associated with Breath odor:

All the drugs that are associated with Breath odor:

Breath odor (1,295 drugs)

Common conditions associated with Breath odor:

All the conditions that are associated with Breath odor:

Breath odor (753 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.