Senna and Pulmonary oedema - a phase IV clinical study of FDA data
Summary:
Pulmonary oedema is found among people who take Senna, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Senna and have Pulmonary oedema. It is created by eHealthMe based on reports of 31,680 people who have side effects when taking Senna from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
31,680 people reported to have side effects when taking Senna.
Among them, 258 people (0.81%) have Pulmonary oedema.
What is Senna?
Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 31,908 Senna users for its effectiveness, alternative drugs and more.
What is Pulmonary oedema?
Pulmonary oedema (fluid accumulation in the lungs) is found to be associated with 2,508 drugs and 1,898 conditions by eHealthMe.
Number of Senna and Pulmonary oedema reports submitted per year:

Time on Senna when people have Pulmonary oedema *:
Gender of people who have Pulmonary oedema when taking Senna*:
Age of people who have Pulmonary oedema when taking Senna *:
Common drugs people take besides Senna *:
Common side effects people have besides Pulmonary oedema *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Senna and have Pulmonary oedema?
Check whether Pulmonary oedema is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Pulmonary oedema and when was it recovered:
Expand to all the drugs that have ingredients of senna:
- Pulmonary oedema and drugs with ingredients of senna (179 reports)
Alternative drugs to, pros and cons of Senna:
- Senna (31,908 reports)
Common Senna side effects:
- Fatigue (feeling of tiredness): 3,033 reports
- Constipation: 2,200 reports
- Pain: 1,942 reports
- Breathing difficulty: 1,899 reports
- Pneumonia: 1,830 reports
- Weakness: 1,790 reports
- Diarrhea: 1,738 reports
- Nausea and vomiting: 1,714 reports
Browse all side effects of Senna:
a b c d e f g h i j k l m n o p q r s t u v w x y zPulmonary oedema treatments and more:
- Pulmonary oedema (47,662 reports)
COVID vaccines that are related to Pulmonary oedema:
- Pulmonary oedema in Moderna COVID Vaccine
- Pulmonary oedema in Pfizer BioNTech Covid Vaccine
- Pulmonary oedema in Johnson and Johnson Covid Vaccine
Common drugs associated with Pulmonary oedema:
- Furosemide: 3,532 reports
- Aspirin: 3,093 reports
- Lasix: 3,037 reports
- Prednisone: 2,672 reports
- Amlodipine: 2,070 reports
- Omeprazole: 1,767 reports
- Humira: 1,706 reports
- Morphine: 1,696 reports
- Metformin: 1,651 reports
- Methotrexate: 1,580 reports
All the drugs that are associated with Pulmonary oedema:
- Pulmonary oedema (2,508 drugs)
Common conditions associated with Pulmonary oedema:
- Primary pulmonary hypertension: 2,848 reports
- High blood pressure: 2,518 reports
- Rheumatoid arthritis: 2,466 reports
- Multiple myeloma: 1,463 reports
- Pain: 1,419 reports
- Diabetes: 1,411 reports
All the conditions that are associated with Pulmonary oedema:
- Pulmonary oedema (1,898 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on senna (the active ingredients of Senna) and Senna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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