Sennosides and Salmonella enterocolitis - a phase IV clinical study of FDA data


Salmonella enterocolitis is reported only by a few people who take Sennosides.

The phase IV clinical study analyzes which people take Sennosides and have Salmonella enterocolitis. It is created by eHealthMe based on reports of 3,453 people who have side effects while taking Sennosides from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

3,453 people reported to have side effects when taking Sennosides.
Among them, 4 people (0.12%) have Salmonella enterocolitis.

What is Sennosides?

Sennosides has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 3,502 Sennosides users for its effectiveness, alternative drugs and more.

What is Salmonella enterocolitis?

Salmonella enterocolitis (an infection in the lining of the small intestine caused by salmonella bacteria) is found to be associated with 750 drugs and 488 conditions by eHealthMe.

Number of Sennosides and Salmonella enterocolitis reports submitted per year:

Could Sennosides cause Salmonella enterocolitis?

Time on Sennosides when people have Salmonella enterocolitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Salmonella enterocolitis when taking Sennosides *:

  • female: 50 %
  • male: 50 %

Age of people who have Salmonella enterocolitis when taking Sennosides *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 50 %

Common drugs people take besides Sennosides *:

  1. Xopenex Hfa: 2 people, 50.00%
  2. Pyridoxine Hcl: 2 people, 50.00%
  3. Ninlaro: 2 people, 50.00%
  4. Nicotine Polacrilex: 2 people, 50.00%
  5. Melatonin: 2 people, 50.00%
  6. Levaquin: 2 people, 50.00%
  7. Exjade: 2 people, 50.00%
  8. Dexlansoprazole: 2 people, 50.00%
  9. Combivent Respimat: 2 people, 50.00%
  10. Amoxicillin And Clavulanate Potassium: 2 people, 50.00%

Common side effects people have besides Salmonella enterocolitis *:

  1. Tenderness (pain or discomfort when an affected area is touched): 2 people, 50.00%
  2. Pneumonia: 2 people, 50.00%
  3. Peripheral Nerve Lesion: 2 people, 50.00%
  4. Pain: 2 people, 50.00%
  5. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 2 people, 50.00%
  6. Fever: 2 people, 50.00%
  7. Device Related Infection: 2 people, 50.00%
  8. Bone Pain: 2 people, 50.00%
  9. Bacteraemia (presence of bacteria in the blood): 2 people, 50.00%
  10. Aspartate Aminotransferase Increased: 2 people, 50.00%

Common conditions people have *:

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 50.00%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 50.00%
  3. Iron Overload: 2 people, 50.00%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 50.00%
  5. Chronic Kidney Disease: 2 people, 50.00%
  6. Cellulitis (infection under the skin): 2 people, 50.00%
  7. Anaemia (lack of blood): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sennosides and have Salmonella enterocolitis?

Check whether Salmonella enterocolitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Sennosides:

Salmonella enterocolitis treatments and more:

COVID vaccines that are related to Salmonella enterocolitis:

How severe was Salmonella enterocolitis and when was it recovered:

Expand to all the drugs that have ingredients of senna:

Common drugs associated with Salmonella enterocolitis:

All the drugs that are associated with Salmonella enterocolitis:

Common conditions associated with Salmonella enterocolitis:

All the conditions that are associated with Salmonella enterocolitis:

How the study uses the data?

The study uses data from the FDA. It is based on senna (the active ingredients of Sennosides) and Sennosides (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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