Seroquel and Oculomucocutaneous syndrome - a phase IV clinical study of FDA data


Oculomucocutaneous syndrome is found among people who take Seroquel, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Seroquel and have Oculomucocutaneous syndrome. It is created by eHealthMe based on reports of 108,921 people who have side effects when taking Seroquel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2022

108,921 people reported to have side effects when taking Seroquel.
Among them, 10 people (0.01%) have Oculomucocutaneous syndrome.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 115,260 Seroquel users for its effectiveness, alternative drugs and more.

What is Oculomucocutaneous syndrome?

Oculomucocutaneous syndrome (a condition characterized by keratoconjunctivitis sicca and by scarring, fibrosis, metaplasia, and shrinkage of the conjunctiva;) is found to be associated with 212 drugs and 177 conditions by eHealthMe.

Number of Seroquel and Oculomucocutaneous syndrome reports submitted per year:

Could Seroquel cause Oculomucocutaneous syndrome?

Time on Seroquel when people have Oculomucocutaneous syndrome *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Oculomucocutaneous syndrome when taking Seroquel *:

  • female: 60 %
  • male: 40 %

Age of people who have Oculomucocutaneous syndrome when taking Seroquel *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 90 %
  • 60+: 0.0 %

Common drugs people take besides Seroquel *:

  1. Lamictal: 4 people, 40.00%
  2. Zantac: 3 people, 30.00%
  3. Voltaren: 3 people, 30.00%
  4. Depakene: 3 people, 30.00%
  5. Xyzal: 3 people, 30.00%
  6. Halcion: 3 people, 30.00%
  7. Lamisil: 3 people, 30.00%
  8. Tenormin: 2 people, 20.00%
  9. Risperdal: 2 people, 20.00%
  10. Micardis: 2 people, 20.00%

Common side effects people have besides Oculomucocutaneous syndrome *:

  1. Rashes (redness): 7 people, 70.00%
  2. Lip Erosion (peeling off of lip): 4 people, 40.00%
  3. Erythema Multiforme (a type of hypersensitivity reaction): 4 people, 40.00%
  4. Fever: 4 people, 40.00%
  5. Stomatitis (inflammation of mucous membrane of mouth): 3 people, 30.00%
  6. Breathing Difficulty: 3 people, 30.00%
  7. C-Reactive Protein Increased: 3 people, 30.00%
  8. Conjunctivitis (pink eye): 3 people, 30.00%
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 30.00%
  10. Enanthema (rash formed inside the body): 3 people, 30.00%

Common conditions people have *:

  1. Stress And Anxiety: 3 people, 30.00%
  2. Sleep Disorder: 3 people, 30.00%
  3. Constipation: 3 people, 30.00%
  4. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 30.00%
  5. Agitation (state of anxiety or nervous excitement): 3 people, 30.00%
  6. Delirium (wild excitement): 2 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and have Oculomucocutaneous syndrome?

Check whether Oculomucocutaneous syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Oculomucocutaneous syndrome and when was it recovered:

Expand to all the drugs that have ingredients of quetiapine fumarate:

Alternative drugs to, pros and cons of Seroquel:

Common Seroquel side effects:

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Oculomucocutaneous syndrome treatments and more:

COVID vaccines that are related to Oculomucocutaneous syndrome:

All the drugs that are associated with Oculomucocutaneous syndrome:

All the conditions that are associated with Oculomucocutaneous syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on quetiapine fumarate (the active ingredients of Seroquel) and Seroquel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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