Sevoflurane and Mental disorder - a phase IV clinical study of FDA data


Mental disorder is found among people who take Sevoflurane, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Sevoflurane and have Mental disorder. It is created by eHealthMe based on reports of 8,466 people who have side effects when taking Sevoflurane from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 28, 2023

8,466 people reported to have side effects when taking Sevoflurane.
Among them, 8 people (0.09%) have Mental disorder.

What is Sevoflurane?

Sevoflurane has active ingredients of sevoflurane. eHealthMe is studying from 8,477 Sevoflurane users for its effectiveness, alternative drugs and more.

What is Mental disorder?

Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability) is found to be associated with 2,402 drugs and 1,656 conditions by eHealthMe.

Number of Sevoflurane and Mental disorder reports submitted per year:

Could Sevoflurane cause Mental disorder?

Time on Sevoflurane when people have Mental disorder *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Mental disorder when taking Sevoflurane *:

  • female: 85.71 %
  • male: 14.29 %

Age of people who have Mental disorder when taking Sevoflurane *:

  • 0-1: 0.0 %
  • 2-9: 14.29 %
  • 10-19: 14.29 %
  • 20-29: 14.29 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 14.29 %
  • 60+: 14.29 %

Common drugs people take besides Sevoflurane *:

  1. Fentanyl: 2 people, 25.00%
  2. Ibuprofen: 2 people, 25.00%
  3. Zofran: 1 person, 12.50%
  4. Heparin: 1 person, 12.50%
  5. Advil: 1 person, 12.50%
  6. Aleve: 1 person, 12.50%
  7. B12: 1 person, 12.50%
  8. Cefazolin Sodium: 1 person, 12.50%
  9. Diprivan: 1 person, 12.50%
  10. Fentanyl Citrate: 1 person, 12.50%

Common side effects people have besides Mental disorder *:

  1. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 25.00%
  2. Stress And Anxiety: 2 people, 25.00%
  3. Loss Of Consciousness: 2 people, 25.00%
  4. Pain: 2 people, 25.00%
  5. Whipple's Disease (infection with a bacteria called tropheryma whippelii): 1 person, 12.50%
  6. Haematocrit Decreased: 1 person, 12.50%
  7. Fever: 1 person, 12.50%
  8. Enlarged Heart: 1 person, 12.50%
  9. Emotional Distress: 1 person, 12.50%
  10. Electrocardiogram T Wave Inversion: 1 person, 12.50%

Common conditions people have *:

  1. General Anaesthesia: 4 people, 50.00%
  2. Pain: 2 people, 25.00%
  3. Anaesthesia: 2 people, 25.00%
  4. Acne (skin problems that cause pimples): 2 people, 25.00%
  5. Thermal Burn (burn by heat): 1 person, 12.50%
  6. Sedation: 1 person, 12.50%
  7. Premenstrual Syndrome: 1 person, 12.50%
  8. Menstrual Disorder (disease of menstrual cycle): 1 person, 12.50%
  9. Maternal Therapy To Enhance Foetal Lung Maturity: 1 person, 12.50%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Sevoflurane and have Mental disorder?

Check whether Mental disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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How the study uses the data?

The study uses data from the FDA. It is based on sevoflurane (the active ingredients of Sevoflurane) and Sevoflurane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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