Simvastatin and Large granular lymphocytosis - a phase IV clinical study of FDA data

Summary:

Large granular lymphocytosis is reported only by a few people who take Simvastatin.

The phase IV clinical study analyzes which people take Simvastatin and have Large granular lymphocytosis. It is created by eHealthMe based on reports of 230,650 people who have side effects while taking Simvastatin from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 04, 2022

230,650 people reported to have side effects when taking Simvastatin.
Among them, 3 people (0.0%) have Large granular lymphocytosis.


What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 238,025 Simvastatin users for its effectiveness, alternative drugs and more.

What is Large granular lymphocytosis?

Large granular lymphocytosis (increased number of large granular white blood cells) is found to be associated with 134 drugs and 69 conditions by eHealthMe.

Number of Simvastatin and Large granular lymphocytosis reports submitted per year:

Could Simvastatin cause Large granular lymphocytosis?

Gender of people who have Large granular lymphocytosis when taking Simvastatin *:

  • female: 100 %
  • male: 0.0 %

Common drugs people take besides Simvastatin *:

  1. Sertraline: 2 people, 66.67%
  2. Prednisone: 2 people, 66.67%
  3. Methotrexate: 2 people, 66.67%
  4. Meclizine: 2 people, 66.67%
  5. Exjade: 2 people, 66.67%
  6. Digoxin: 2 people, 66.67%
  7. Cytoxan: 2 people, 66.67%
  8. Benazepril Hydrochloride: 2 people, 66.67%
  9. Aranesp: 2 people, 66.67%
  10. Aggrenox: 2 people, 66.67%

Common side effects people have besides Large granular lymphocytosis *:

  1. Weakness: 2 people, 66.67%
  2. Haemoglobin Decreased: 2 people, 66.67%
  3. Fever: 2 people, 66.67%
  4. Aplasia Pure Red Cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells): 2 people, 66.67%

Common conditions people have *:

  1. Anaemia Of Malignant Disease: 2 people, 66.67%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and have Large granular lymphocytosis?

Check whether Large granular lymphocytosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Large granular lymphocytosis and when was it recovered:

Expand to all the drugs that have ingredients of simvastatin:

Alternative drugs to, pros and cons of Simvastatin:

Common Simvastatin side effects:

Browse all side effects of Simvastatin:

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Large granular lymphocytosis treatments and more:

COVID vaccines that are related to Large granular lymphocytosis:

All the drugs that are associated with Large granular lymphocytosis:

All the conditions that are associated with Large granular lymphocytosis:

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Simvastatin) and Simvastatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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