Sodium bicarbonate and Brain herniation - a phase IV clinical study of FDA data

Summary:

Brain herniation is found among people who take Sodium bicarbonate, especially for people who are female, 30-39 old.

The phase IV clinical study analyzes which people take Sodium bicarbonate and have Brain herniation. It is created by eHealthMe based on reports of 22,013 people who have side effects when taking Sodium bicarbonate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 17, 2022

22,013 people reported to have side effects when taking Sodium bicarbonate.
Among them, 16 people (0.07%) have Brain herniation.


What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 19,645 Sodium bicarbonate users for its effectiveness, alternative drugs and more.

What is Brain herniation?

Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull) is found to be associated with 1,163 drugs and 830 conditions by eHealthMe.

Number of Sodium bicarbonate and Brain herniation reports submitted per year:

Could Sodium bicarbonate cause Brain herniation?

Gender of people who have Brain herniation when taking Sodium bicarbonate *:

  • female: 80 %
  • male: 20 %

Age of people who have Brain herniation when taking Sodium bicarbonate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 13.33 %
  • 20-29: 13.33 %
  • 30-39: 40.0 %
  • 40-49: 0.0 %
  • 50-59: 6.67 %
  • 60+: 26.67 %

Common drugs people take besides Sodium bicarbonate *:

  1. Methotrexate: 5 people, 31.25%
  2. Dexamethasone: 4 people, 25.00%
  3. Calcium: 3 people, 18.75%
  4. Insulin: 3 people, 18.75%
  5. Propofol: 3 people, 18.75%
  6. Leucovorin Calcium: 3 people, 18.75%
  7. Zosyn: 2 people, 12.50%
  8. Arthrotec: 2 people, 12.50%
  9. Azithromycin: 2 people, 12.50%
  10. Cefazolin: 2 people, 12.50%

Common side effects people have besides Brain herniation *:

  1. Unresponsive To Stimuli: 5 people, 31.25%
  2. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 5 people, 31.25%
  3. Brain Compression: 3 people, 18.75%
  4. Drug Ineffective: 3 people, 18.75%
  5. Drug Toxicity: 3 people, 18.75%
  6. Hypoxic-Ischaemic Encephalopathy (condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total): 3 people, 18.75%
  7. Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 2 people, 12.50%
  8. Consciousness - Decreased: 2 people, 12.50%
  9. Haemorrhage Intracranial (bleeding within the skull): 2 people, 12.50%
  10. Completed Suicide (act of taking one's own life): 2 people, 12.50%

Common conditions people have *:

  1. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 4 people, 25.00%
  2. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 2 people, 12.50%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 12.50%
  4. Sedation: 2 people, 12.50%
  5. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 2 people, 12.50%
  6. Lactic Acidosis (low ph in body tissues): 2 people, 12.50%
  7. Hypokalemia (low potassium): 2 people, 12.50%
  8. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 2 people, 12.50%
  9. Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 2 people, 12.50%
  10. Completed Suicide (act of taking one's own life): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Sodium bicarbonate and have Brain herniation?

Check whether Brain herniation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

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Alternative drugs to, pros and cons of Sodium bicarbonate:

Common Sodium bicarbonate side effects:

Browse all side effects of Sodium bicarbonate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Brain herniation treatments and more:

COVID vaccines that are related to Brain herniation:

Common drugs associated with Brain herniation:

All the drugs that are associated with Brain herniation:

Common conditions associated with Brain herniation:

All the conditions that are associated with Brain herniation:

How the study uses the data?

The study uses data from the FDA. It is based on sodium bicarbonate (the active ingredients of Sodium bicarbonate) and Sodium bicarbonate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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