Solu-medrol and Guillain barre syndrome - a phase IV clinical study of FDA data

Summary:

We study 36,773 people who have side effects when taking Solu-medrol. Guillain barre syndrome is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Heparin and have Malignant melanoma.

The phase IV clinical study analyzes which people take Solu-medrol and have Guillain barre syndrome. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

36,773 people reported to have side effects when taking Solu-medrol.
Among them, 31 people (0.08%) have Guillain barre syndrome.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is used in multiple sclerosis. Currently, eHealthMe is studying from 36,917 Solu-medrol users.

What is Guillain barre syndrome?

Guillain barre syndrome (the body's immune system attacks its peripheral nervous system) is found to be associated with 1,465 drugs and 948 conditions by eHealthMe. Currently, we are studying 6,925 people who have Guillain barre syndrome.

Number of Solu-medrol and Guillain barre syndrome reports submitted per year:

Could Solu-medrol cause Guillain barre syndrome?

Time on Solu-medrol when people have Guillain barre syndrome *:

Gender of people who have Guillain barre syndrome when taking Solu-medrol *:

female: 37.93 %
male: 62.07 %

Age of people who have Guillain barre syndrome when taking Solu-medrol *:

Common drugs people take besides Solu-medrol *:

Common side effects people have besides Guillain barre syndrome *:

Weakness: 7 people, 22.58%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 19.35%
Breathing Difficulty: 4 people, 12.90%
Erythema Multiforme (a type of hypersensitivity reaction): 4 people, 12.90%
Pituitary Cyst: 4 people, 12.90%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 4 people, 12.90%
Drug Hypersensitivity: 4 people, 12.90%
Abdominal Pain Upper: 4 people, 12.90%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 4 people, 12.90%
Loss Of Consciousness: 4 people, 12.90%

Common conditions people have *:

Prostate Cancer: 3 people, 9.68%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 3 people, 9.68%
Malignant Melanoma (skin cancer rises from melancytes): 3 people, 9.68%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 6.45%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.45%
Non-Small Cell Lung Cancer Recurrent (type of epithelial lung cancer reoccurrence): 2 people, 6.45%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 6.45%
Bronchial Carcinoma (lung cancer): 1 person, 3.23%
Itching: 1 person, 3.23%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Solu-medrol and have Guillain barre syndrome?

Check whether Guillain barre syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Solu-medrol side effects by duration, gender and age:

Solu-medrol side effects (36,917 reports)

Guillain barre syndrome treatments and more:

Guillain barre syndrome (6,925 reports)

Common drugs associated with Guillain barre syndrome:

All the drugs that are associated with Guillain barre syndrome:

Guillain barre syndrome (1,465 drugs)

Common conditions associated with Guillain barre syndrome:

All the conditions that are associated with Guillain barre syndrome:

Guillain barre syndrome (948 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylprednisolone sodium succinate (the active ingredients of Solu-medrol) and Solu-medrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.