Spironolactone and hydrochlorothiazide and Kidney failure - from FDA reports


Kidney failure is reported only by a few people who take Spironolactone And Hydrochlorothiazide. We study 136 people who have side effects while taking Spironolactone and hydrochlorothiazide from FDA. Among them, 4 have Kidney failure. Find out below who they are, when they have Kidney failure and more.



On Jul, 11, 2018

136 people reported to have side effects when taking Spironolactone and hydrochlorothiazide.
Among them, 4 people (2.94%) have Kidney failure


Number of reports submitted per year:

Could Spironolactone and hydrochlorothiazide cause Kidney failure?

Gender of people who have Kidney failure when taking Spironolactone and hydrochlorothiazide *:

  • female: 50 %
  • male: 50 %

Age of people who have Kidney failure when taking Spironolactone and hydrochlorothiazide *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25 %
  • 60+: 75 %

Top conditions involved for these people *:

  1. Type 2 Diabetes: 1 person, 25.00%
  2. Mitral Valve Replacement: 1 person, 25.00%
  3. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 25.00%
  4. Back Pain: 1 person, 25.00%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 25.00%

Top co-used drugs for these people *:

  1. Trasylol: 2 people, 50.00%
  2. Nitroglycerin: 2 people, 50.00%
  3. Heparin: 2 people, 50.00%
  4. Warfarin Sodium: 1 person, 25.00%
  5. Bumex: 1 person, 25.00%

Top other side effects for these people *:

  1. Stress And Anxiety: 2 people, 50.00%
  2. Nausea (feeling of having an urge to vomit): 2 people, 50.00%
  3. Depression: 2 people, 50.00%
  4. Injury: 2 people, 50.00%
  5. Emotional Distress: 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

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Related studies

Spironolactone and hydrochlorothiazide

Spironolactone and hydrochlorothiazide has active ingredients of hydrochlorothiazide; spironolactone. It is often used in swelling. (latest outcomes from Spironolactone and hydrochlorothiazide 151 users)

Kidney failure

Kidney failure (loss of kidney function) has been reported by people with high blood pressure, multiple myeloma, coronary artery bypass, diabetes, rheumatoid arthritis (latest reports from 87,302 Kidney failure patients).


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What would happen?

Predict new side effects and undetected conditions when you take Spironolactone and hydrochlorothiazide and have Kidney failure


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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