Spironolactone and Cardiac failure - a phase IV clinical study of FDA data
We study 110,029 people who have side effects when taking Spironolactone. Cardiac failure is found, especially among people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Furosemide and have Primary pulmonary hypertension.
The phase IV clinical study analyzes which people take Spironolactone and have Cardiac failure. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
110,029 people reported to have side effects when taking Spironolactone.
Among them, 3,981 people (3.62%) have Cardiac failure.
What is Spironolactone?
Spironolactone has active ingredients of spironolactone. It is used in acne. Currently, eHealthMe is studying from 113,624 Spironolactone users.
What is Cardiac failure?
Cardiac failure is found to be associated with 2,641 drugs and 2,169 conditions by eHealthMe. Currently, we are studying 139,176 people who have Cardiac failure.
Number of Spironolactone and Cardiac failure reports submitted per year:
Time on Spironolactone when people have Cardiac failure *:
Gender of people who have Cardiac failure when taking Spironolactone*:
Age of people who have Cardiac failure when taking Spironolactone *:
Common drugs people take besides Spironolactone *:
Common side effects people have besides Cardiac failure *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Spironolactone and have Cardiac failure?Check whether Cardiac failure is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Spironolactone side effects by duration, gender and age:
- Spironolactone side effects (113,624 reports)
Cardiac failure treatments and more:
- Cardiac failure (139,176 reports)
Common drugs associated with Cardiac failure:
- Furosemide: 8,202 reports
- Lasix: 5,662 reports
- Aspirin: 4,989 reports
- Entresto: 4,446 reports
- Spironolactone: 3,981 reports
- Metformin: 3,234 reports
- Allopurinol: 3,136 reports
- Lopurin: 3,136 reports
- Digoxin: 2,946 reports
- Prednisone: 2,925 reports
All the drugs that are associated with Cardiac failure:
- Cardiac failure (2,641 drugs)
Common conditions associated with Cardiac failure:
- High blood pressure: 5,543 reports
- Primary pulmonary hypertension: 4,007 reports
- Atrial fibrillation/flutter: 3,555 reports
- Rheumatoid arthritis: 3,335 reports
- Diabetes: 3,205 reports
- Multiple myeloma: 2,367 reports
- Type 2 diabetes: 2,118 reports
All the conditions that are associated with Cardiac failure:
- Cardiac failure (2,169 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on spironolactone (the active ingredients of Spironolactone) and Spironolactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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