Spironolactone and Liver tenderness - a phase IV clinical study of FDA data

Summary:

Liver tenderness is reported only by a few people who take Spironolactone.

The phase IV clinical study analyzes which people take Spironolactone and have Liver tenderness. It is created by eHealthMe based on reports of 88,511 people who have side effects while taking Spironolactone from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Aug, 05, 2022

88,511 people reported to have side effects when taking Spironolactone.
Among them, 3 people (0.0%) have Liver tenderness.


What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 91,530 Spironolactone users for its effectiveness, alternative drugs and more.

What is Liver tenderness?

Liver tenderness (pain and discomfort in liver when touched) is found to be associated with 374 drugs and 204 conditions by eHealthMe.

Number of Spironolactone and Liver tenderness reports submitted per year:

Could Spironolactone cause Liver tenderness?

Gender of people who have Liver tenderness when taking Spironolactone *:

  • female: 33.33 %
  • male: 66.67 %

Age of people who have Liver tenderness when taking Spironolactone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 33.33 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 0.0 %

Common drugs people take besides Spironolactone *:

  1. Tylenol: 1 person, 33.33%
  2. Tracleer: 1 person, 33.33%
  3. Sildenafil Citrate: 1 person, 33.33%
  4. Prednisone: 1 person, 33.33%
  5. Nystatin: 1 person, 33.33%
  6. Methotrexate: 1 person, 33.33%
  7. Mavyret: 1 person, 33.33%
  8. Lasix: 1 person, 33.33%
  9. Coumadin: 1 person, 33.33%

Common side effects people have besides Liver tenderness *:

  1. Abdominal Pain: 2 people, 66.67%
  2. Breathing Difficulty: 2 people, 66.67%
  3. White Blood Cell Count Decreased: 1 person, 33.33%
  4. Heart Rate Irregular: 1 person, 33.33%
  5. Fatigue (feeling of tiredness): 1 person, 33.33%
  6. Fever: 1 person, 33.33%
  7. Gallbladder Disorder: 1 person, 33.33%
  8. Haematocrit Decreased: 1 person, 33.33%
  9. Haemoglobin Decreased: 1 person, 33.33%
  10. Haptoglobin Increased: 1 person, 33.33%

Common conditions people have *:

  1. Hepatitis C: 1 person, 33.33%
  2. Cardiac Failure: 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and have Liver tenderness?

Check whether Liver tenderness is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of Spironolactone:

Liver tenderness treatments and more:

COVID vaccines that are related to Liver tenderness:

How severe was Liver tenderness and when was it recovered:

Expand to all the drugs that have ingredients of spironolactone:

All the drugs that are associated with Liver tenderness:

All the conditions that are associated with Liver tenderness:

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone (the active ingredients of Spironolactone) and Spironolactone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: