Suboxone and Streptococcal infection - a phase IV clinical study of FDA data


Streptococcal infection is reported only by a few people who take Suboxone.

The phase IV clinical study analyzes which people take Suboxone and have Streptococcal infection. It is created by eHealthMe based on reports of 26,417 people who have side effects while taking Suboxone from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

26,417 people reported to have side effects when taking Suboxone.
Among them, 4 people (0.02%) have Streptococcal infection.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 29,166 Suboxone users for its effectiveness, alternative drugs and more.

What is Streptococcal infection?

Streptococcal infection is found to be associated with 1,133 drugs and 643 conditions by eHealthMe.

Number of Suboxone and Streptococcal infection reports submitted per year:

Could Suboxone cause Streptococcal infection?

Time on Suboxone when people have Streptococcal infection *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Streptococcal infection when taking Suboxone *:

  • female: 75 %
  • male: 25 %

Age of people who have Streptococcal infection when taking Suboxone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 25 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 25 %
  • 50-59: 50 %
  • 60+: 0.0 %

Common drugs people take besides Suboxone *:

  1. Valium: 2 people, 50.00%
  2. Detrol La: 2 people, 50.00%
  3. Zofran: 1 person, 25.00%
  4. Azithromycin: 1 person, 25.00%
  5. Effexor: 1 person, 25.00%
  6. Dilaudid: 1 person, 25.00%
  7. Depo-Provera: 1 person, 25.00%
  8. Compazine: 1 person, 25.00%
  9. Bunavail: 1 person, 25.00%
  10. Augmentin '125': 1 person, 25.00%

Common side effects people have besides Streptococcal infection *:

  1. Sinusitis (inflammation of sinus): 3 people, 75.00%
  2. Gingival Pain (gum pain): 2 people, 50.00%
  3. Tooth Loss: 2 people, 50.00%
  4. Tooth Fracture: 2 people, 50.00%
  5. Oral Discomfort (pain or irritation in mouth): 2 people, 50.00%
  6. Back Pain: 2 people, 50.00%
  7. Dental Caries: 2 people, 50.00%
  8. Stress And Anxiety: 2 people, 50.00%
  9. Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 50.00%
  10. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 50.00%

Common conditions people have *:

  1. Stress And Anxiety: 2 people, 50.00%
  2. Quit Smoking: 2 people, 50.00%
  3. Pain: 2 people, 50.00%
  4. Cystitis Interstitial (unknown cause characterized by bladder pain): 2 people, 50.00%
  5. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 25.00%
  6. Drug Dependence: 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Suboxone and have Streptococcal infection?

Check whether Streptococcal infection is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Streptococcal infection and when was it recovered:

Expand to all the drugs that have ingredients of buprenorphine hydrochloride; naloxone hydrochloride:

Alternative drugs to, pros and cons of Suboxone:

Common Suboxone side effects:

Browse all side effects of Suboxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Streptococcal infection treatments and more:

COVID vaccines that are related to Streptococcal infection:

Common drugs associated with Streptococcal infection:

All the drugs that are associated with Streptococcal infection:

Common conditions associated with Streptococcal infection:

All the conditions that are associated with Streptococcal infection:

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine hydrochloride; naloxone hydrochloride (the active ingredients of Suboxone) and Suboxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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