Sulfasalazine and Earache - a phase IV clinical study of FDA data


Earache is reported only by a few people who take Sulfasalazine.

The phase IV clinical study analyzes which people take Sulfasalazine and have Earache. It is created by eHealthMe based on reports of 67,897 people who have side effects while taking Sulfasalazine from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 01, 2022

67,897 people reported to have side effects when taking Sulfasalazine.
Among them, 5 people (0.01%) have Earache.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 68,893 Sulfasalazine users for its effectiveness, alternative drugs and more.

What is Earache?

Earache (ear pain) is found to be associated with 629 drugs by eHealthMe.

Number of Sulfasalazine and Earache reports submitted per year:

Could Sulfasalazine cause Earache?

Gender of people who have Earache when taking Sulfasalazine *:

  • female: 80 %
  • male: 20 %

Age of people who have Earache when taking Sulfasalazine *:

  • 0-1: 0.0 %
  • 2-9: 20 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 40 %
  • 50-59: 40 %
  • 60+: 0.0 %

Common drugs people take besides Sulfasalazine *:

  1. Enbrel: 5 people, 100.00%
  2. Prednisone: 3 people, 60.00%
  3. Methotrexate: 2 people, 40.00%
  4. Famotidine: 1 person, 20.00%
  5. Alprazolam: 1 person, 20.00%
  6. Amlodipine: 1 person, 20.00%
  7. Budesonide: 1 person, 20.00%
  8. Calcium: 1 person, 20.00%
  9. Celecoxib: 1 person, 20.00%
  10. Cromolyn Sodium: 1 person, 20.00%

Common side effects people have besides Earache *:

  1. Tooth Abscess (pus formation in tooth): 1 person, 20.00%
  2. Throat Irritation: 1 person, 20.00%
  3. Nasopharyngitis (inflammation of the nasopharynx): 1 person, 20.00%
  4. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 20.00%
  5. Joint Stiffness: 1 person, 20.00%
  6. Fever: 1 person, 20.00%
  7. Face Oedema (swelling of face): 1 person, 20.00%
  8. Difficulty In Walking: 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfasalazine and have Earache?

Check whether Earache is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Sulfasalazine:

Earache treatments and more:

COVID vaccines that are related to Earache:

How severe was Earache and when was it recovered:

Expand to all the drugs that have ingredients of sulfasalazine:

All the drugs that are associated with Earache:

All the conditions that are associated with Earache:

How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine (the active ingredients of Sulfasalazine) and Sulfasalazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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