Sumatriptan and Gastric ulcer - a phase IV clinical study of FDA data


Gastric ulcer is found among people who take Sumatriptan, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Sumatriptan and have Gastric ulcer. It is created by eHealthMe based on reports of 12,010 people who have side effects when taking Sumatriptan from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 25, 2022

12,010 people reported to have side effects when taking Sumatriptan.
Among them, 38 people (0.32%) have Gastric ulcer.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 12,904 Sumatriptan users for its effectiveness, alternative drugs and more.

What is Gastric ulcer?

Gastric ulcer (stomach ulcer) is found to be associated with 3,325 drugs and 3,124 conditions by eHealthMe.

Number of Sumatriptan and Gastric ulcer reports submitted per year:

Could Sumatriptan cause Gastric ulcer?

Time on Sumatriptan when people have Gastric ulcer *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastric ulcer when taking Sumatriptan *:

  • female: 86.11 %
  • male: 13.89 %

Age of people who have Gastric ulcer when taking Sumatriptan *:

  • 0-1: 0.0 %
  • 2-9: 3.03 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.06 %
  • 40-49: 30.3 %
  • 50-59: 48.48 %
  • 60+: 12.12 %

Common drugs people take besides Sumatriptan *:

  1. Neurontin: 11 people, 28.95%
  2. Fosamax: 10 people, 26.32%
  3. Aredia: 10 people, 26.32%
  4. Zometa: 8 people, 21.05%
  5. Ambien: 7 people, 18.42%
  6. Gabapentin: 7 people, 18.42%
  7. Prozac: 6 people, 15.79%
  8. Aspirin: 6 people, 15.79%
  9. Ibuprofen: 6 people, 15.79%
  10. Ondansetron: 5 people, 13.16%

Common side effects people have besides Gastric ulcer *:

  1. Nausea (feeling of having an urge to vomit): 15 people, 39.47%
  2. Oedema Peripheral (superficial swelling): 13 people, 34.21%
  3. Anaemia (lack of blood): 13 people, 34.21%
  4. Depression: 13 people, 34.21%
  5. Hypoaesthesia (reduced sense of touch or sensation): 12 people, 31.58%
  6. Pain: 11 people, 28.95%
  7. Tooth Disorder (tooth disease): 10 people, 26.32%
  8. Dental Caries: 8 people, 21.05%
  9. Emotional Distress: 8 people, 21.05%
  10. Diarrhea: 8 people, 21.05%

Common conditions people have *:

  1. Pain: 5 people, 13.16%
  2. Insomnia (sleeplessness): 4 people, 10.53%
  3. Osteoporosis (bones weak and more likely to break): 4 people, 10.53%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.89%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.26%
  6. Discomfort: 2 people, 5.26%
  7. Breast Cancer Metastatic: 2 people, 5.26%
  8. Granulocyte Count Decreased: 2 people, 5.26%
  9. Breast Cancer: 2 people, 5.26%
  10. High Blood Cholesterol: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan and have Gastric ulcer?

Check whether Gastric ulcer is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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Common conditions associated with Gastric ulcer:

All the conditions that are associated with Gastric ulcer:

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate (the active ingredients of Sumatriptan) and Sumatriptan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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