Tazidime and Cardiomyopathy - a phase IV clinical study of FDA data

Summary:

Cardiomyopathy is found among people who take Tazidime, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Tazidime and have Cardiomyopathy. It is created by eHealthMe based on reports of 8,930 people who have side effects when taking Tazidime from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Mar, 24, 2023

8,930 people reported to have side effects when taking Tazidime.
Among them, 37 people (0.41%) have Cardiomyopathy.


What is Tazidime?

Tazidime has active ingredients of ceftazidime. eHealthMe is studying from 8,950 Tazidime users for its effectiveness, alternative drugs and more.

What is Cardiomyopathy?

Cardiomyopathy (weakening of the heart muscle) is found to be associated with 1,966 drugs and 1,182 conditions by eHealthMe.

Number of Tazidime and Cardiomyopathy reports submitted per year:

Could Tazidime cause Cardiomyopathy?

Time on Tazidime when people have Cardiomyopathy *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Cardiomyopathy when taking Tazidime *:

  • female: 74.29 %
  • male: 25.71 %

Age of people who have Cardiomyopathy when taking Tazidime *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 25.71 %
  • 20-29: 5.71 %
  • 30-39: 0.0 %
  • 40-49: 2.86 %
  • 50-59: 11.43 %
  • 60+: 54.29 %

Common drugs people take besides Tazidime *:

  1. Vancomycin: 14 people, 37.84%
  2. Cellcept: 12 people, 32.43%
  3. Ondansetron: 10 people, 27.03%
  4. Lasix: 8 people, 21.62%
  5. Toradol: 7 people, 18.92%
  6. Ambien: 7 people, 18.92%
  7. Aspirin: 7 people, 18.92%
  8. Benadryl: 7 people, 18.92%
  9. Carvedilol: 7 people, 18.92%
  10. Coreg: 7 people, 18.92%

Common side effects people have besides Cardiomyopathy *:

  1. Ejection Fraction Decreased (systolic heart failure): 19 people, 51.35%
  2. Cardiac Failure: 14 people, 37.84%
  3. Arrhythmias (irregular heartbeat): 10 people, 27.03%
  4. Breathing Difficulty: 10 people, 27.03%
  5. Hepatic Steatosis (fatty liver disease): 9 people, 24.32%
  6. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 9 people, 24.32%
  7. Oedema Peripheral (superficial swelling): 9 people, 24.32%
  8. Cardiac Failure Congestive: 9 people, 24.32%
  9. Renal Cyst (kidney cyst): 9 people, 24.32%
  10. Fatigue (feeling of tiredness): 9 people, 24.32%

Common conditions people have *:

  1. Nausea (feeling of having an urge to vomit): 12 people, 32.43%
  2. Febrile Neutropenia (fever with reduced white blood cells): 12 people, 32.43%
  3. Bone Marrow Conditioning Regimen: 12 people, 32.43%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 12 people, 32.43%
  5. Fever: 5 people, 13.51%
  6. Pneumonia: 4 people, 10.81%
  7. Hiv Infection: 4 people, 10.81%
  8. High Blood Pressure: 2 people, 5.41%
  9. Peripartum Cardiomyopathy (deterioration in cardiac function presenting typically between the last month of pregnancy and up to five months postpartum): 1 person, 2.70%
  10. Lymphoma (cancer that begins in immune system cells): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Tazidime and have Cardiomyopathy?

Check whether Cardiomyopathy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

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How severe was Cardiomyopathy and when was it recovered:

Expand to all the drugs that have ingredients of ceftazidime:

Alternative drugs to, pros and cons of Tazidime:

Common Tazidime side effects:

Browse all side effects of Tazidime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Cardiomyopathy treatments and more:

COVID vaccines that are related to Cardiomyopathy:

Common drugs associated with Cardiomyopathy:

All the drugs that are associated with Cardiomyopathy:

Common conditions associated with Cardiomyopathy:

All the conditions that are associated with Cardiomyopathy:

How the study uses the data?

The study uses data from the FDA. It is based on ceftazidime (the active ingredients of Tazidime) and Tazidime (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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