Thiamine hcl and Eosinophilia - a phase IV clinical study of FDA data

Summary:

Eosinophilia is reported only by a few people who take Thiamine Hcl.

The phase IV clinical study analyzes which people take Thiamine hcl and have Eosinophilia. It is created by eHealthMe based on reports of 887 people who have side effects while taking Thiamine hcl from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Dec, 07, 2022

887 people reported to have side effects when taking Thiamine hcl.
Among them, 2 people (0.23%) have Eosinophilia.


What is Thiamine hcl?

Thiamine hcl has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 896 Thiamine hcl users for its effectiveness, alternative drugs and more.

What is Eosinophilia?

Eosinophilia (eosinophil count in the peripheral blood exceeds) is found to be associated with 1,619 drugs and 1,326 conditions by eHealthMe.

Number of Thiamine hcl and Eosinophilia reports submitted per year:

Could Thiamine hcl cause Eosinophilia?

Gender of people who have Eosinophilia when taking Thiamine hcl *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Eosinophilia when taking Thiamine hcl *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

Common drugs people take besides Thiamine hcl *:

  1. Valproate Sodium: 1 person, 50.00%
  2. Risperdal Consta: 1 person, 50.00%
  3. Olanzapine: 1 person, 50.00%
  4. Clozapine: 1 person, 50.00%
  5. Citalopram Hydrobromide: 1 person, 50.00%
  6. Celecoxib: 1 person, 50.00%

Common side effects people have besides Eosinophilia *:

  1. Urinary Tract Infection: 1 person, 50.00%
  2. Type Iv Hypersensitivity Reaction (delayed type hypersensitivity as the reaction takes two to three days to develop): 1 person, 50.00%
  3. Troponin Increased: 1 person, 50.00%
  4. Red Blood Cell Sedimentation Rate Increased: 1 person, 50.00%
  5. Red Blood Cell Count Increased: 1 person, 50.00%
  6. Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 1 person, 50.00%
  7. Leukopenia (less number of white blood cells in blood): 1 person, 50.00%
  8. Leukocytosis (increased white blood cells): 1 person, 50.00%
  9. Hypotension (abnormally low blood pressure): 1 person, 50.00%
  10. Hyperhidrosis (abnormally increased sweating): 1 person, 50.00%

Common conditions people have *:

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 50.00%
  2. Back Pain: 1 person, 50.00%
  3. Affective Disorder (mental disorder): 1 person, 50.00%
  4. Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine hcl and have Eosinophilia?

Check whether Eosinophilia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

How severe was Eosinophilia and when was it recovered:

Expand to all the drugs that have ingredients of thiamine (vitamin b1):

Alternative drugs to, pros and cons of Thiamine hcl:

Eosinophilia treatments and more:

COVID vaccines that are related to Eosinophilia:

Common drugs associated with Eosinophilia:

All the drugs that are associated with Eosinophilia:

Common conditions associated with Eosinophilia:

All the conditions that are associated with Eosinophilia:

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine hcl) and Thiamine hcl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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