Thiamine and Skin discoloration - bluish - a phase IV clinical study of FDA data


Skin discoloration - bluish is found among people who take Thiamine, especially for people who are male, 60+ old.

The phase IV clinical study analyzes which people take Thiamine and have Skin discoloration - bluish. It is created by eHealthMe based on reports of 9,266 people who have side effects when taking Thiamine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

9,266 people reported to have side effects when taking Thiamine.
Among them, 12 people (0.13%) have Skin discoloration - bluish.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 9,349 Thiamine users for its effectiveness, alternative drugs and more.

What is Skin discoloration - bluish?

Skin discoloration - bluish (bluish colour of skin) is found to be associated with 2,379 drugs and 2,039 conditions by eHealthMe.

Number of Thiamine and Skin discoloration - bluish reports submitted per year:

Could Thiamine cause Skin discoloration - bluish?

Gender of people who have Skin discoloration - bluish when taking Thiamine *:

  • female: 36.36 %
  • male: 63.64 %

Age of people who have Skin discoloration - bluish when taking Thiamine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 40 %
  • 40-49: 0.0 %
  • 50-59: 10 %
  • 60+: 50 %

Common drugs people take besides Thiamine *:

  1. Invega Sustenna: 2 people, 16.67%
  2. Invega: 2 people, 16.67%
  3. Seroquel: 2 people, 16.67%
  4. Apixaban: 2 people, 16.67%
  5. Sertraline: 2 people, 16.67%
  6. Benadryl: 2 people, 16.67%
  7. Digoxin: 1 person, 8.33%
  8. Demerol: 1 person, 8.33%
  9. Diazepam: 1 person, 8.33%
  10. Differin: 1 person, 8.33%

Common side effects people have besides Skin discoloration - bluish *:

  1. Breathing Difficulty: 4 people, 33.33%
  2. Nausea And Vomiting: 3 people, 25.00%
  3. Memory Loss: 3 people, 25.00%
  4. Malaise (a feeling of general discomfort or uneasiness): 3 people, 25.00%
  5. Head Injury: 3 people, 25.00%
  6. Fall: 2 people, 16.67%
  7. Nausea (feeling of having an urge to vomit): 2 people, 16.67%
  8. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 2 people, 16.67%
  9. Hypotension (abnormally low blood pressure): 2 people, 16.67%
  10. Hyperhidrosis (abnormally increased sweating): 2 people, 16.67%

Common conditions people have *:

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 16.67%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 8.33%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%
  4. Cardiac Disorder: 1 person, 8.33%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 8.33%
  6. Diabetes: 1 person, 8.33%
  7. Gout (uric acid crystals building up in the body): 1 person, 8.33%
  8. High Blood Pressure: 1 person, 8.33%
  9. Hostility: 1 person, 8.33%
  10. Hyperthyroidism (over activity of the thyroid gland): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine and have Skin discoloration - bluish?

Check whether Skin discoloration - bluish is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Skin discoloration - bluish and when was it recovered:

Expand to all the drugs that have ingredients of thiamine (vitamin b1):

Alternative drugs to, pros and cons of Thiamine:

Common Thiamine side effects:

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Skin discoloration - bluish treatments and more:

COVID vaccines that are related to Skin discoloration - bluish:

Common drugs associated with Skin discoloration - bluish:

All the drugs that are associated with Skin discoloration - bluish:

Common conditions associated with Skin discoloration - bluish:

All the conditions that are associated with Skin discoloration - bluish:

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine) and Thiamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: