Thyrogen and Salivary gland enlargement - a phase IV clinical study of FDA data


Salivary gland enlargement is reported only by a few people who take Thyrogen.

The phase IV clinical study analyzes which people take Thyrogen and have Salivary gland enlargement. It is created by eHealthMe based on reports of 971 people who have side effects while taking Thyrogen from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Aug, 08, 2022

971 people reported to have side effects when taking Thyrogen.
Among them, 4 people (0.41%) have Salivary gland enlargement.

What is Thyrogen?

Thyrogen has active ingredients of thyrotropin alfa. eHealthMe is studying from 902 Thyrogen users for its effectiveness, alternative drugs and more.

What is Salivary gland enlargement?

Salivary gland enlargement (increased size of salivary gland) is found to be associated with 660 drugs and 304 conditions by eHealthMe.

Number of Thyrogen and Salivary gland enlargement reports submitted per year:

Could Thyrogen cause Salivary gland enlargement?

Time on Thyrogen when people have Salivary gland enlargement *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Salivary gland enlargement when taking Thyrogen *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Salivary gland enlargement when taking Thyrogen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25 %
  • 60+: 75 %

Common drugs people take besides Thyrogen *:

  1. Synthroid: 3 people, 75.00%
  2. Meclizine: 3 people, 75.00%
  3. Lyrica: 3 people, 75.00%
  4. Lisinopril: 3 people, 75.00%
  5. Lipitor: 3 people, 75.00%
  6. Januvia: 3 people, 75.00%
  7. Fortamet: 3 people, 75.00%
  8. Diovan: 3 people, 75.00%
  9. Demadex: 3 people, 75.00%
  10. Atenolol: 3 people, 75.00%

Common side effects people have besides Salivary gland enlargement *:

  1. Fall: 3 people, 75.00%
  2. Fainting (loss of consciousness and postural tone): 3 people, 75.00%
  3. Aptyalism (deficiency or absence of saliva): 3 people, 75.00%
  4. Dehydration (dryness resulting from the removal of water): 3 people, 75.00%
  5. Dry Mouth: 3 people, 75.00%
  6. Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 3 people, 75.00%
  7. Acute Kidney Failure: 3 people, 75.00%
  8. Nosebleed (bleeding from nose): 3 people, 75.00%
  9. Iodine Uptake Increased: 2 people, 50.00%
  10. Gastroenteritis (inflammation of stomach and intestine): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Thyrogen and have Salivary gland enlargement?

Check whether Salivary gland enlargement is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Thyrogen:

Salivary gland enlargement treatments and more:

COVID vaccines that are related to Salivary gland enlargement:

How severe was Salivary gland enlargement and when was it recovered:

Expand to all the drugs that have ingredients of thyrotropin alfa:

All the drugs that are associated with Salivary gland enlargement:

All the conditions that are associated with Salivary gland enlargement:

How the study uses the data?

The study uses data from the FDA. It is based on thyrotropin alfa (the active ingredients of Thyrogen) and Thyrogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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