Tofranil and Hyperhidrosis - a phase IV clinical study of FDA data


We study 1,920 people who have side effects when taking Tofranil. Hyperhidrosis is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Prozac and have High blood cholesterol.

The phase IV clinical study analyzes which people take Tofranil and have Hyperhidrosis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

On Sep, 25, 2023

1,920 people reported to have side effects when taking Tofranil.
Among them, 43 people (2.24%) have Hyperhidrosis.

What is Tofranil?

Tofranil has active ingredients of imipramine hydrochloride. It is used in depression. Currently, eHealthMe is studying from 1,999 Tofranil users.

What is Hyperhidrosis?

Hyperhidrosis (abnormally increased sweating) is found to be associated with 3,835 drugs and 3,479 conditions by eHealthMe. Currently, we are studying 140,194 people who have Hyperhidrosis.

Number of Tofranil and Hyperhidrosis reports submitted per year:

Could Tofranil cause Hyperhidrosis?

Time on Tofranil when people have Hyperhidrosis *:

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Gender of people who have Hyperhidrosis when taking Tofranil*:

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Age of people who have Hyperhidrosis when taking Tofranil *:

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Common drugs people take besides Tofranil *:

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Common side effects people have besides Hyperhidrosis *:

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Common conditions people have *:

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* Approximation only. Some reports may have incomplete information.

Do you take Tofranil and have Hyperhidrosis?

Check whether Hyperhidrosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Hyperhidrosis and when was it recovered:

Expand to all the drugs that have ingredients of imipramine hydrochloride:

Alternative drugs to, pros and cons of Tofranil:

Browse all side effects of Tofranil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hyperhidrosis treatments and more:

Common drugs associated with Hyperhidrosis:

All the drugs that are associated with Hyperhidrosis:

Common conditions associated with Hyperhidrosis:

All the conditions that are associated with Hyperhidrosis:

How the study uses the data?

The study uses data from the FDA. It is based on imipramine hydrochloride (the active ingredients of Tofranil) and Tofranil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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