Topamax and Failure to thrive - a phase IV clinical study of FDA data

Summary:

Failure to thrive is found among people who take Topamax, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Topamax and have Failure to thrive. It is created by eHealthMe based on reports of 50,397 people who have side effects when taking Topamax from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

50,397 people reported to have side effects when taking Topamax.
Among them, 40 people (0.08%) have Failure to thrive.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 55,045 Topamax users for its effectiveness, alternative drugs and more.

What is Failure to thrive?

Failure to thrive (inadequate weight gain and physical growth in children) is found to be associated with 1,662 drugs and 1,079 conditions by eHealthMe.

Number of Topamax and Failure to thrive reports submitted per year:

Time on Topamax when people have Failure to thrive *:

Gender of people who have Failure to thrive when taking Topamax *:

female: 41.03 %
male: 58.97 %

Age of people who have Failure to thrive when taking Topamax *:

Common drugs people take besides Topamax *:

Zoloft: 12 people, 30.00%
Ibuprofen: 7 people, 17.50%
Prevacid: 7 people, 17.50%
Folic Acid: 6 people, 15.00%
Elavil: 5 people, 12.50%
Zomig: 5 people, 12.50%
Heparin: 5 people, 12.50%
Sertraline Hydrochloride: 5 people, 12.50%
Ventolin: 5 people, 12.50%
Prozac: 4 people, 10.00%

Common side effects people have besides Failure to thrive *:

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 32.50%
Weight Decreased: 12 people, 30.00%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 8 people, 20.00%
Otitis Media (inflammation of the middle ear): 7 people, 17.50%
Premature Baby: 7 people, 17.50%
Cardiac Failure Congestive: 6 people, 15.00%
Asthma: 6 people, 15.00%
Pulmonary Artery Atresia (lungs artery absent): 6 people, 15.00%
Pneumonia: 6 people, 15.00%
Aortic Valve Incompetence: 5 people, 12.50%

Common conditions people have *:

Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 18 people, 45.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 17.50%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 5 people, 12.50%
Headache (pain in head): 2 people, 5.00%
Back Pain: 2 people, 5.00%
Bleeding Disorders: 2 people, 5.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 5.00%
Depression: 2 people, 5.00%
Allergic Rhinitis: 2 people, 5.00%
Infantile Spasms: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Topamax and have Failure to thrive?

Check whether Failure to thrive is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .

Related studies

How severe was Failure to thrive and when was it recovered:

Failure to thrive in Topamax

Expand to all the drugs that have ingredients of topiramate:

Failure to thrive and drugs with ingredients of topiramate (61 reports)

Alternative drugs to, pros and cons of Topamax:

Topamax (55,045 reports)

Common Topamax side effects:

Drug ineffective: 3,806 reports
Headache (pain in head): 3,666 reports
Fatigue (feeling of tiredness): 3,199 reports
Pain: 2,850 reports
Stress and anxiety: 2,584 reports
Dizziness: 2,506 reports

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Failure to thrive treatments and more:

Failure to thrive (7,512 reports)

COVID vaccines that are related to Failure to thrive:

Common drugs associated with Failure to thrive:

All the drugs that are associated with Failure to thrive:

Failure to thrive (1,662 drugs)

Common conditions associated with Failure to thrive:

All the conditions that are associated with Failure to thrive:

Failure to thrive (1,079 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topamax) and Topamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.