Topamax and Verbal abuse - a phase IV clinical study of FDA data


Verbal abuse is found among people who take Topamax, especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Topamax and have Verbal abuse. It is created by eHealthMe based on reports of 50,397 people who have side effects when taking Topamax from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2022

50,397 people reported to have side effects when taking Topamax.
Among them, 6 people (0.01%) have Verbal abuse.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 55,008 Topamax users for its effectiveness, alternative drugs and more.

What is Verbal abuse?

Verbal abuse (abusive behaviour involving the use of language) is found to be associated with 354 drugs and 210 conditions by eHealthMe.

Number of Topamax and Verbal abuse reports submitted per year:

Could Topamax cause Verbal abuse?

Time on Topamax when people have Verbal abuse *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Verbal abuse when taking Topamax *:

  • female: 40 %
  • male: 60 %

Age of people who have Verbal abuse when taking Topamax *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 20 %
  • 30-39: 0.0 %
  • 40-49: 40 %
  • 50-59: 20 %
  • 60+: 20 %

Common drugs people take besides Topamax *:

  1. Zyprexa: 1 person, 16.67%
  2. Zolpidem: 1 person, 16.67%
  3. Lactulose: 1 person, 16.67%
  4. Klonopin: 1 person, 16.67%
  5. Increlex: 1 person, 16.67%
  6. Haldol: 1 person, 16.67%
  7. Glucotrol: 1 person, 16.67%
  8. Famotidine: 1 person, 16.67%
  9. Epidiolex: 1 person, 16.67%
  10. Effexor: 1 person, 16.67%

Common side effects people have besides Verbal abuse *:

  1. Abnormal Behavior: 3 people, 50.00%
  2. Agitation (state of anxiety or nervous excitement): 3 people, 50.00%
  3. Irritability: 2 people, 33.33%
  4. Aggression: 2 people, 33.33%
  5. Stress And Anxiety: 2 people, 33.33%
  6. Depression: 1 person, 16.67%
  7. Ill-Defined Disorder: 1 person, 16.67%
  8. Hypomania (a mild form of mania, marked by elation and hyperactivity): 1 person, 16.67%
  9. High Blood Pressure: 1 person, 16.67%
  10. Hallucinations (sensations that appear real but are created by your mind): 1 person, 16.67%

Common conditions people have *:

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 16.67%
  2. Psychotic Disorder: 1 person, 16.67%
  3. Failure To Thrive (inadequate weight gain and physical growth in children): 1 person, 16.67%
  4. Depressive Symptom: 1 person, 16.67%
  5. Depression: 1 person, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Topamax and have Verbal abuse?

Check whether Verbal abuse is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Verbal abuse and when was it recovered:

Expand to all the drugs that have ingredients of topiramate:

Alternative drugs to, pros and cons of Topamax:

Common Topamax side effects:

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Verbal abuse treatments and more:

COVID vaccines that are related to Verbal abuse:

All the drugs that are associated with Verbal abuse:

All the conditions that are associated with Verbal abuse:

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topamax) and Topamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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