Topiramate and Gastrointestinal inflammation - a phase IV clinical study of FDA data


Gastrointestinal inflammation is found among people who take Topiramate, especially for people who are female, 50-59 old.

The phase IV clinical study analyzes which people take Topiramate and have Gastrointestinal inflammation. It is created by eHealthMe based on reports of 39,034 people who have side effects when taking Topiramate from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 16, 2022

39,034 people reported to have side effects when taking Topiramate.
Among them, 8 people (0.02%) have Gastrointestinal inflammation.

What is Topiramate?

Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 35,686 Topiramate users for its effectiveness, alternative drugs and more.

What is Gastrointestinal inflammation?

Gastrointestinal inflammation (inflammation of stomach and intestine) is found to be associated with 772 drugs and 511 conditions by eHealthMe.

Number of Topiramate and Gastrointestinal inflammation reports submitted per year:

Could Topiramate cause Gastrointestinal inflammation?

Gender of people who have Gastrointestinal inflammation when taking Topiramate *:

  • female: 87.5 %
  • male: 12.5 %

Age of people who have Gastrointestinal inflammation when taking Topiramate *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 12.5 %
  • 30-39: 12.5 %
  • 40-49: 12.5 %
  • 50-59: 37.5 %
  • 60+: 25.0 %

Common drugs people take besides Topiramate *:

  1. Levothyroxine Sodium: 3 people, 37.50%
  2. Nitroglycerin: 2 people, 25.00%
  3. Prednisolone: 2 people, 25.00%
  4. Meclizine: 2 people, 25.00%
  5. Lidocaine: 2 people, 25.00%
  6. Montelukast Sodium: 2 people, 25.00%
  7. Nasacort: 2 people, 25.00%
  8. Desonide: 2 people, 25.00%
  9. Ofloxacin: 2 people, 25.00%
  10. Ketoconazole: 2 people, 25.00%

Common side effects people have besides Gastrointestinal inflammation *:

  1. Urinary Tract Infection: 3 people, 37.50%
  2. Dizziness: 3 people, 37.50%
  3. Eyelid Infection: 2 people, 25.00%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 25.00%
  5. Colitis (inflammation of colon): 2 people, 25.00%
  6. Infusion Site Pruritus (severe itching at infusion site): 2 people, 25.00%
  7. Influenza Like Illness: 2 people, 25.00%
  8. Erythema Migrans (lyme disease develop a red rash): 2 people, 25.00%
  9. Dehydration (dryness resulting from the removal of water): 2 people, 25.00%
  10. Nausea And Vomiting: 2 people, 25.00%

Common conditions people have *:

  1. Primary Immunodeficiency Syndrome: 2 people, 25.00%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 12.50%
  3. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 12.50%
  4. Impaired Gastric Emptying: 1 person, 12.50%
  5. Immune System Disorder: 1 person, 12.50%
  6. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 12.50%
  7. Diarrhea: 1 person, 12.50%
  8. Breast Cancer Metastatic: 1 person, 12.50%
  9. Breakthrough Pain: 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Topiramate and have Gastrointestinal inflammation?

Check whether Gastrointestinal inflammation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Gastrointestinal inflammation and when was it recovered:

Expand to all the drugs that have ingredients of topiramate:

Alternative drugs to, pros and cons of Topiramate:

Common Topiramate side effects:

Browse all side effects of Topiramate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Gastrointestinal inflammation treatments and more:

COVID vaccines that are related to Gastrointestinal inflammation:

Common drugs associated with Gastrointestinal inflammation:

All the drugs that are associated with Gastrointestinal inflammation:

Common conditions associated with Gastrointestinal inflammation:

All the conditions that are associated with Gastrointestinal inflammation:

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topiramate) and Topiramate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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