Topiramate and Sinusitis - a phase IV clinical study of FDA data

Summary:

We study 44,093 people who have side effects when taking Topiramate. Sinusitis is found, especially among people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take Vitamin d3 and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people take Topiramate and have Sinusitis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

44,093 people reported to have side effects when taking Topiramate.
Among them, 521 people (1.18%) have Sinusitis.

What is Topiramate?

Topiramate has active ingredients of topiramate. It is used in migraine. Currently, eHealthMe is studying from 45,740 Topiramate users.

What is Sinusitis?

Sinusitis (inflammation of sinus) is found to be associated with 3,433 drugs and 2,611 conditions by eHealthMe. Currently, we are studying 143,797 people who have Sinusitis.

Number of Topiramate and Sinusitis reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Topiramate and have Sinusitis?

Check whether Sinusitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .

Related studies

Topiramate side effects by duration, gender and age:

Topiramate side effects (45,740 reports)

Sinusitis treatments and more:

Sinusitis (143,797 reports)

Common drugs associated with Sinusitis:

All the drugs that are associated with Sinusitis:

Sinusitis (3,433 drugs)

Common conditions associated with Sinusitis:

Rheumatoid arthritis: 23,148 reports
Asthma: 6,250 reports
Multiple sclerosis: 6,162 reports
Psoriasis: 5,495 reports
Crohn's disease: 3,958 reports

All the conditions that are associated with Sinusitis:

Sinusitis (2,611 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topiramate) and Topiramate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.