Topotecan and Hemiplegia - a phase IV clinical study of FDA data


Hemiplegia is reported only by a few people who take Topotecan.

The phase IV clinical study analyzes which people take Topotecan and have Hemiplegia. It is created by eHealthMe based on reports of 5,065 people who have side effects while taking Topotecan from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 19, 2022

5,065 people reported to have side effects when taking Topotecan.
Among them, 4 people (0.08%) have Hemiplegia.

What is Topotecan?

Topotecan has active ingredients of topotecan hydrochloride. eHealthMe is studying from 5,076 Topotecan users for its effectiveness, alternative drugs and more.

What is Hemiplegia?

Hemiplegia (paralysis of one side of the body) is found to be associated with 1,517 drugs and 1,047 conditions by eHealthMe.

Number of Topotecan and Hemiplegia reports submitted per year:

Could Topotecan cause Hemiplegia?

Gender of people who have Hemiplegia when taking Topotecan *:

  • female: 25 %
  • male: 75 %

Age of people who have Hemiplegia when taking Topotecan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Topotecan *:

  1. Thalomid: 2 people, 50.00%
  2. Pepcid: 2 people, 50.00%
  3. Lasix: 2 people, 50.00%
  4. Dilantin: 2 people, 50.00%
  5. Decadron: 2 people, 50.00%
  6. Coumadin: 2 people, 50.00%
  7. Atenolol: 2 people, 50.00%
  8. Prochlorperazine: 1 person, 25.00%
  9. Oxazepam: 1 person, 25.00%
  10. Fentanyl: 1 person, 25.00%

Common side effects people have besides Hemiplegia *:

  1. Thrombocytopenia (decrease of platelets in blood): 2 people, 50.00%
  2. Cerebral Infarction (less blood supply to brain resulting tissue damage): 2 people, 50.00%
  3. Venous Thrombosis Deep Limb (blood clot that forms in a vein deep in the limb): 1 person, 25.00%
  4. Thrombotic Thrombocytopenic Purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 1 person, 25.00%
  5. Speech Impairment (Adult) (inability to speak (adult)): 1 person, 25.00%
  6. Pleural Effusion (water on the lungs): 1 person, 25.00%
  7. Metastases To Breast (cancer spreads to brain): 1 person, 25.00%
  8. Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 1 person, 25.00%
  9. Distress: 1 person, 25.00%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 25.00%

Common conditions people have *:

  1. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Topotecan and have Hemiplegia?

Check whether Hemiplegia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Hemiplegia and when was it recovered:

Expand to all the drugs that have ingredients of topotecan hydrochloride:

Alternative drugs to, pros and cons of Topotecan:

Common Topotecan side effects:

Browse all side effects of Topotecan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hemiplegia treatments and more:

COVID vaccines that are related to Hemiplegia:

Common drugs associated with Hemiplegia:

All the drugs that are associated with Hemiplegia:

Common conditions associated with Hemiplegia:

All the conditions that are associated with Hemiplegia:

How the study uses the data?

The study uses data from the FDA. It is based on topotecan hydrochloride (the active ingredients of Topotecan) and Topotecan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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