Who have Interstitial lung disease with Topotecan - from FDA reports


Interstitial lung disease is found among people who take Topotecan, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Fluorouracil, and have Colon cancer. This study is created by eHealthMe based on reports of 3,537 people who have side effects when taking Topotecan from FDA, and is updated regularly.

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On Feb, 11, 2019

3,537 people reported to have side effects when taking Topotecan.
Among them, 45 people (1.27%) have Interstitial lung disease


Number of reports submitted per year:

Could Topotecan cause Interstitial lung disease?

Time on Topotecan when people have Interstitial lung disease *:

  • < 1 month: 41.94 %
  • 1 - 6 months: 51.61 %
  • 6 - 12 months: 3.23 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 3.23 %
  • 10+ years: 0.0 %

Gender of people who have Interstitial lung disease when taking Topotecan *:

  • female: 51.28 %
  • male: 48.72 %

Age of people who have Interstitial lung disease when taking Topotecan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 18.42 %
  • 60+: 81.58 %

Top conditions involved for these people *:

  1. Colon Cancer: 21 people, 46.67%
  2. Preventive Health Care: 8 people, 17.78%
  3. Lung Cancer - Small Cell (lung cancer): 7 people, 15.56%
  4. Nausea (feeling of having an urge to vomit): 6 people, 13.33%
  5. Upper Respiratory Tract Infection: 5 people, 11.11%
  6. Respiratory Tract Congestion (blockage on respiratory system): 5 people, 11.11%
  7. High Blood Pressure: 5 people, 11.11%
  8. Ovarian Cancer (cancer of ovary): 5 people, 11.11%
  9. Constipation: 4 people, 8.89%
  10. Diabetes: 4 people, 8.89%

Top co-used drugs for these people *:

  1. Fluorouracil: 18 people, 40.00%
  2. Decadron: 8 people, 17.78%
  3. Diovan: 7 people, 15.56%
  4. Levoleucovorin Calcium: 7 people, 15.56%
  5. Aspirin: 6 people, 13.33%
  6. Imodium: 5 people, 11.11%
  7. Avandia: 5 people, 11.11%
  8. Glucotrol Xl: 5 people, 11.11%
  9. Phenergan: 5 people, 11.11%
  10. Mucinex: 5 people, 11.11%

Top other side effects for these people *:

  1. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 10 people, 22.22%
  2. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 13.33%
  3. Colon Cancer: 6 people, 13.33%
  4. Cardiac Failure Congestive: 5 people, 11.11%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 8.89%
  6. Disease Progression: 4 people, 8.89%
  7. Rashes (redness): 4 people, 8.89%
  8. Dry Skin: 3 people, 6.67%
  9. Nausea (feeling of having an urge to vomit): 3 people, 6.67%
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you have Interstitial lung disease while taking Topotecan?


You are not alone:




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Topotecan side effects

Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Browse all side effects of Topotecan
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What would happen?

Predict new side effects and undetected conditions when you take Topotecan and have Interstitial lung disease


FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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