Toprol-xl and Abnormal behavior - a phase IV clinical study of FDA data
Summary:
We study 38,273 people who have side effects when taking Toprol-xl. Abnormal behavior is found, especially among people who are female, 50-59 old, have been taking the drug for < 1 month, also take Chantix and have High blood cholesterol.
The phase IV clinical study analyzes which people take Toprol-xl and have Abnormal behavior. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
38,273 people reported to have side effects when taking Toprol-xl.
Among them, 142 people (0.37%) have Abnormal behavior.
What is Toprol-xl?
Toprol-xl has active ingredients of metoprolol succinate. It is used in high blood pressure. Currently, eHealthMe is studying from 40,608 Toprol-xl users.
What is Abnormal behavior?
Abnormal behavior is found to be associated with 2,443 drugs and 1,763 conditions by eHealthMe. Currently, we are studying 49,988 people who have Abnormal behavior.
Number of Toprol-xl and Abnormal behavior reports submitted per year:

Time on Toprol-xl when people have Abnormal behavior *:
Gender of people who have Abnormal behavior when taking Toprol-xl*:
Age of people who have Abnormal behavior when taking Toprol-xl *:
Common drugs people take besides Toprol-xl *:
Common side effects people have besides Abnormal behavior *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Toprol-xl and have Abnormal behavior?
Check whether Abnormal behavior is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Toprol-xl side effects by duration, gender and age:
- Toprol-xl side effects (40,608 reports)
Abnormal behavior treatments and more:
- Abnormal behavior (49,988 reports)
Common drugs associated with Abnormal behavior:
- Chantix: 2,500 reports
- Nuplazid: 1,559 reports
- Tamiflu: 1,382 reports
- Seroquel: 1,376 reports
- Singulair: 1,345 reports
- Abilify: 1,322 reports
- Clonazepam: 1,274 reports
- Strattera: 1,252 reports
- Cymbalta: 1,158 reports
- Risperdal: 1,158 reports
All the drugs that are associated with Abnormal behavior:
- Abnormal behavior (2,443 drugs)
Common conditions associated with Abnormal behavior:
- Depression: 2,972 reports
- Attention deficit hyperactivity disorder: 2,722 reports
- Quit smoking: 1,984 reports
All the conditions that are associated with Abnormal behavior:
- Abnormal behavior (1,763 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on metoprolol succinate (the active ingredients of Toprol-xl) and Toprol-xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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