Toprol-xl and Postural orthostatic tachycardia syndrome - a phase IV clinical study of FDA data

Summary:

Postural orthostatic tachycardia syndrome is found among people who take Toprol-xl, especially for people who are female, 20-29 old.

The phase IV clinical study analyzes which people take Toprol-xl and have Postural orthostatic tachycardia syndrome. It is created by eHealthMe based on reports of 38,272 people who have side effects when taking Toprol-xl from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

38,272 people reported to have side effects when taking Toprol-xl.
Among them, 9 people (0.02%) have Postural orthostatic tachycardia syndrome.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,590 Toprol-xl users for its effectiveness, alternative drugs and more.

What is Postural orthostatic tachycardia syndrome?

Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright) is found to be associated with 561 drugs and 264 conditions by eHealthMe.

Number of Toprol-xl and Postural orthostatic tachycardia syndrome reports submitted per year:

Could Toprol-xl cause Postural orthostatic tachycardia syndrome?

Gender of people who have Postural orthostatic tachycardia syndrome when taking Toprol-xl *:

female: 100 %
male: 0.0 %

Age of people who have Postural orthostatic tachycardia syndrome when taking Toprol-xl *:

Common drugs people take besides Toprol-xl *:

Common side effects people have besides Postural orthostatic tachycardia syndrome *:

Heart Rate Irregular: 5 people, 55.56%
Dizziness: 3 people, 33.33%
Myopathy (a muscular disease in which the muscle fibres do not function): 3 people, 33.33%
Muscle Function Loss: 3 people, 33.33%
Fainting (loss of consciousness and postural tone): 3 people, 33.33%
Heart Attack: 3 people, 33.33%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 22.22%
Pain: 2 people, 22.22%
Hypokalemia (low potassium): 2 people, 22.22%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 2 people, 22.22%

Common conditions people have *:

Premenstrual Syndrome: 3 people, 33.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 22.22%
Urinary Tract Infection: 1 person, 11.11%
Rickets (softening of bones): 1 person, 11.11%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 11.11%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 1 person, 11.11%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 11.11%
Fatigue (feeling of tiredness): 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Toprol-xl and have Postural orthostatic tachycardia syndrome?

Check whether Postural orthostatic tachycardia syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Postural orthostatic tachycardia syndrome and when was it recovered:

Postural orthostatic tachycardia syndrome in Toprol-xl

Expand to all the drugs that have ingredients of metoprolol succinate:

Postural orthostatic tachycardia syndrome and drugs with ingredients of metoprolol succinate

Alternative drugs to, pros and cons of Toprol-xl:

Toprol-xl (40,590 reports)

Common Toprol-xl side effects:

High blood pressure: 3,354 reports
Fatigue (feeling of tiredness): 2,995 reports
Breathing difficulty: 2,923 reports
Pain: 2,876 reports
Weakness: 2,857 reports
Dizziness: 2,749 reports

Browse all side effects of Toprol-xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Postural orthostatic tachycardia syndrome treatments and more:

Postural orthostatic tachycardia syndrome (1,842 reports)

COVID vaccines that are related to Postural orthostatic tachycardia syndrome:

Common drugs associated with Postural orthostatic tachycardia syndrome:

Xyrem: 167 reports

All the drugs that are associated with Postural orthostatic tachycardia syndrome:

Postural orthostatic tachycardia syndrome (561 drugs)

Common conditions associated with Postural orthostatic tachycardia syndrome:

Narcolepsy: 160 reports

All the conditions that are associated with Postural orthostatic tachycardia syndrome:

Postural orthostatic tachycardia syndrome (264 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoprolol succinate (the active ingredients of Toprol-xl) and Toprol-xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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