Tracleer and Teeth brittle - a phase IV clinical study of FDA data


Teeth brittle is reported only by a few people who take Tracleer.

The phase IV clinical study analyzes which people take Tracleer and have Teeth brittle. It is created by eHealthMe based on reports of 54,348 people who have side effects while taking Tracleer from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 19, 2022

54,348 people reported to have side effects when taking Tracleer.
Among them, 3 people (0.01%) have Teeth brittle.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 54,408 Tracleer users for its effectiveness, alternative drugs and more.

What is Teeth brittle?

Teeth brittle (other half has a defect in the teeth) is found to be associated with 532 drugs and 289 conditions by eHealthMe.

Number of Tracleer and Teeth brittle reports submitted per year:

Could Tracleer cause Teeth brittle?

Gender of people who have Teeth brittle when taking Tracleer *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Teeth brittle when taking Tracleer *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Tracleer *:

  1. Ventavis: 2 people, 66.67%
  2. Riociguat: 2 people, 66.67%
  3. Letairis: 2 people, 66.67%
  4. Coumadin: 2 people, 66.67%
  5. Victrelis: 1 person, 33.33%
  6. Peg-Intron: 1 person, 33.33%

Common side effects people have besides Teeth brittle *:

  1. Tooth Fracture: 3 people, 100.00%
  2. Weakness: 3 people, 100.00%
  3. Stress And Anxiety: 3 people, 100.00%
  4. Breathing Difficulty: 3 people, 100.00%
  5. Malaise (a feeling of general discomfort or uneasiness): 3 people, 100.00%
  6. Depression: 3 people, 100.00%
  7. Acute Upper Airway Obstruction (blockage occurs in the upper airway): 2 people, 66.67%
  8. Oedema Peripheral (superficial swelling): 2 people, 66.67%
  9. Dyspnea Exertional: 2 people, 66.67%
  10. Lip Swelling: 2 people, 66.67%

Common conditions people have *:

  1. Hepatitis C: 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Tracleer and have Teeth brittle?

Check whether Teeth brittle is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Teeth brittle and when was it recovered:

Expand to all the drugs that have ingredients of bosentan:

Alternative drugs to, pros and cons of Tracleer:

Common Tracleer side effects:

Browse all side effects of Tracleer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Teeth brittle treatments and more:

COVID vaccines that are related to Teeth brittle:

All the drugs that are associated with Teeth brittle:

All the conditions that are associated with Teeth brittle:

How the study uses the data?

The study uses data from the FDA. It is based on bosentan (the active ingredients of Tracleer) and Tracleer (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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