Trazodone hydrochloride and Enlarged heart - a phase IV clinical study of FDA data
Summary:
Enlarged heart is found among people who take Trazodone hydrochloride, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months.
The phase IV clinical study analyzes which people take Trazodone hydrochloride and have Enlarged heart. It is created by eHealthMe based on reports of 15,045 people who have side effects when taking Trazodone hydrochloride from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
15,045 people reported to have side effects when taking Trazodone hydrochloride.
Among them, 49 people (0.33%) have Enlarged heart.
What is Trazodone hydrochloride?
Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 20,294 Trazodone hydrochloride users for its effectiveness, alternative drugs and more.
What is Enlarged heart?
Enlarged heart is found to be associated with 2,370 drugs and 1,607 conditions by eHealthMe.
Number of Trazodone hydrochloride and Enlarged heart reports submitted per year:

Time on Trazodone hydrochloride when people have Enlarged heart *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 100 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Enlarged heart when taking Trazodone hydrochloride *:
- female: 77.55 %
- male: 22.45 %
Age of people who have Enlarged heart when taking Trazodone hydrochloride *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 2.7 %
- 30-39: 0.0 %
- 40-49: 29.73 %
- 50-59: 24.32 %
- 60+: 43.24 %
Common drugs people take besides Trazodone hydrochloride *:
- Zometa: 27 people, 55.10%
- Dexamethasone: 17 people, 34.69%
- Oxycontin: 14 people, 28.57%
- Celebrex: 14 people, 28.57%
- Simvastatin: 13 people, 26.53%
- Xanax: 12 people, 24.49%
- Compazine: 12 people, 24.49%
- Levaquin: 12 people, 24.49%
- Aredia: 11 people, 22.45%
- Nexium: 11 people, 22.45%
Common side effects people have besides Enlarged heart *:
- Pain: 32 people, 65.31%
- Stress And Anxiety: 31 people, 63.27%
- Osteonecrosis Of Jaw (death of bone of jaw): 27 people, 55.10%
- Atelectasis (partial or complete collapse of the lung): 24 people, 48.98%
- Chest Pain: 23 people, 46.94%
- Pleural Effusion (water on the lungs): 22 people, 44.90%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 21 people, 42.86%
- Anaemia (lack of blood): 21 people, 42.86%
- Back Pain: 21 people, 42.86%
- Breathing Difficulty: 20 people, 40.82%
Common conditions people have *:
- Metastases To Bone (cancer spreads to bone): 11 people, 22.45%
- Diabetes: 6 people, 12.24%
- High Blood Cholesterol: 6 people, 12.24%
- Breast Cancer Metastatic: 6 people, 12.24%
- Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 5 people, 10.20%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 10.20%
- Osteoporosis (bones weak and more likely to break): 5 people, 10.20%
- Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 5 people, 10.20%
- Pain: 5 people, 10.20%
- Oedema (fluid collection in tissue): 4 people, 8.16%
* Approximation only. Some reports may have incomplete information.
Do you take Trazodone hydrochloride and have Enlarged heart?
Check whether Enlarged heart is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Enlarged heart and when was it recovered:
Expand to all the drugs that have ingredients of trazodone hydrochloride:
Alternative drugs to, pros and cons of Trazodone hydrochloride:
- Trazodone hydrochloride (20,294 reports)
Common Trazodone hydrochloride side effects:
- Fatigue (feeling of tiredness): 1,407 reports
- Drug ineffective: 1,297 reports
- Diarrhea: 1,040 reports
- Pain: 985 reports
- Headache (pain in head): 945 reports
- Insomnia (sleeplessness): 808 reports
Browse all side effects of Trazodone hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zEnlarged heart treatments and more:
- Enlarged heart (18,848 reports)
COVID vaccines that are related to Enlarged heart:
- Enlarged heart in Moderna COVID Vaccine
- Enlarged heart in Pfizer BioNTech Covid Vaccine
- Enlarged heart in Johnson and Johnson Covid Vaccine
Common drugs associated with Enlarged heart:
- Aspirin: 1,837 reports
- Furosemide: 1,687 reports
- Lasix: 1,608 reports
- Vioxx: 1,475 reports
- Prednisone: 1,444 reports
- Zometa: 1,418 reports
- Digoxin: 1,301 reports
- Lipitor: 1,019 reports
- Lisinopril: 995 reports
- Coumadin: 942 reports
All the drugs that are associated with Enlarged heart:
- Enlarged heart (2,370 drugs)
Common conditions associated with Enlarged heart:
- High blood pressure: 1,330 reports
- Depression: 1,105 reports
- Multiple myeloma: 728 reports
- Pain: 727 reports
- Diabetes: 722 reports
- Rheumatoid arthritis: 706 reports
- Osteoporosis: 700 reports
All the conditions that are associated with Enlarged heart:
- Enlarged heart (1,607 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on trazodone hydrochloride (the active ingredients of Trazodone hydrochloride) and Trazodone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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