Trileptal and Depressed level of consciousness - a phase IV clinical study of FDA data
We study 21,453 people who have side effects when taking Trileptal. Depressed level of consciousness is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Keppra and have Depression.
The phase IV clinical study analyzes which people take Trileptal and have Depressed level of consciousness. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
21,453 people reported to have side effects when taking Trileptal.
Among them, 97 people (0.45%) have Depressed level of consciousness.
What is Trileptal?
Trileptal has active ingredients of oxcarbazepine. It is used in bipolar disorder. Currently, eHealthMe is studying from 22,978 Trileptal users.
What is Depressed level of consciousness?
Depressed level of consciousness is found to be associated with 2,584 drugs and 1,976 conditions by eHealthMe. Currently, we are studying 51,796 people who have Depressed level of consciousness.
Number of Trileptal and Depressed level of consciousness reports submitted per year:
Time on Trileptal when people have Depressed level of consciousness *:
- < 1 month: 40 %
- 1 - 6 months: 10 %
- 6 - 12 months: 10 %
- 1 - 2 years: 20 %
- 2 - 5 years: 20 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Depressed level of consciousness when taking Trileptal *:
- female: 59.14 %
- male: 40.86 %
Age of people who have Depressed level of consciousness when taking Trileptal *:
- 0-1: 1.2 %
- 2-9: 3.61 %
- 10-19: 9.64 %
- 20-29: 9.64 %
- 30-39: 8.43 %
- 40-49: 19.28 %
- 50-59: 14.46 %
- 60+: 33.73 %
Common drugs people take besides Trileptal *:
- Keppra: 14 people, 14.43%
- Ambien: 8 people, 8.25%
- Ativan: 8 people, 8.25%
- Depakote: 8 people, 8.25%
- Levothyroxine Sodium: 7 people, 7.22%
- Lamictal: 7 people, 7.22%
- Neurontin: 6 people, 6.19%
- Seroquel: 6 people, 6.19%
- Klonopin: 6 people, 6.19%
- Topamax: 5 people, 5.15%
Common side effects people have besides Depressed level of consciousness *:
- Drowsiness: 22 people, 22.68%
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 19 people, 19.59%
- Fatigue (feeling of tiredness): 17 people, 17.53%
- Sedation: 13 people, 13.40%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 12 people, 12.37%
- Nausea And Vomiting: 11 people, 11.34%
- Breathing Difficulty: 11 people, 11.34%
- Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 11 people, 11.34%
- Swallowing Difficulty: 11 people, 11.34%
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 10 people, 10.31%
Common conditions people have *:
- Depression: 10 people, 10.31%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 6.19%
- Stress And Anxiety: 5 people, 5.15%
- Pain: 5 people, 5.15%
- Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 4 people, 4.12%
- Mood Swings (an extreme or rapid change in mood): 4 people, 4.12%
- Lump In The Abdomen (an area of swelling or growth on abdomen): 4 people, 4.12%
- Sedation: 3 people, 3.09%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 3.09%
- High Blood Pressure: 3 people, 3.09%
* Approximation only. Some reports may have incomplete information.
Do you take Trileptal and have Depressed level of consciousness?Check whether Depressed level of consciousness is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Trileptal side effects by duration, gender and age:
- Trileptal side effects (22,978 reports)
Depressed level of consciousness treatments and more:
- Depressed level of consciousness (51,796 reports)
Common drugs associated with Depressed level of consciousness:
- Furosemide: 2,239 reports
- Aspirin: 1,971 reports
- Morphine: 1,963 reports
- Omeprazole: 1,713 reports
- Amlodipine: 1,634 reports
- Acetaminophen: 1,474 reports
- Loraz: 1,337 reports
- Lorazepam: 1,336 reports
- Diazepam: 1,283 reports
- Lasix: 1,281 reports
All the drugs that are associated with Depressed level of consciousness:
- Depressed level of consciousness (2,584 drugs)
Common conditions associated with Depressed level of consciousness:
- High blood pressure: 2,438 reports
- Pain: 2,233 reports
- Depression: 1,677 reports
- Insomnia: 1,036 reports
- Constipation: 817 reports
- Diabetes: 746 reports
All the conditions that are associated with Depressed level of consciousness:
- Depressed level of consciousness (1,976 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on oxcarbazepine (the active ingredients of Trileptal) and Trileptal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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