Trileptal and Myelodysplastic syndrome - a phase IV clinical study of FDA data

Summary:

Myelodysplastic syndrome is reported only by a few people who take Trileptal.

The phase IV clinical study analyzes which people take Trileptal and have Myelodysplastic syndrome. It is created by eHealthMe based on reports of 20,140 people who have side effects while taking Trileptal from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 22, 2022

20,140 people reported to have side effects when taking Trileptal.
Among them, 4 people (0.02%) have Myelodysplastic syndrome.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 21,590 Trileptal users for its effectiveness, alternative drugs and more.

What is Myelodysplastic syndrome?

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged) is found to be associated with 1,255 drugs and 957 conditions by eHealthMe.

Number of Trileptal and Myelodysplastic syndrome reports submitted per year:

Could Trileptal cause Myelodysplastic syndrome?

Time on Trileptal when people have Myelodysplastic syndrome *:

Gender of people who have Myelodysplastic syndrome when taking Trileptal *:

female: 100 %
male: 0.0 %

Age of people who have Myelodysplastic syndrome when taking Trileptal *:

Common drugs people take besides Trileptal *:

Common side effects people have besides Myelodysplastic syndrome *:

Anaemia (lack of blood): 3 people, 75.00%
Constipation: 3 people, 75.00%
Emotional Distress: 3 people, 75.00%
Stress And Anxiety: 3 people, 75.00%
Fall: 3 people, 75.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 50.00%
Biliary Dilatation: 2 people, 50.00%
Depression: 2 people, 50.00%
Dizziness: 2 people, 50.00%
Atelectasis (partial or complete collapse of the lung): 2 people, 50.00%

Common conditions people have *:

Stress And Anxiety: 1 person, 25.00%
Simple Partial Seizures (seizures which affect only a small region of the brain): 1 person, 25.00%
Post-Traumatic Stress Disorder: 1 person, 25.00%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Trileptal and have Myelodysplastic syndrome?

Check whether Myelodysplastic syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .

Related studies

Alternative drugs to, pros and cons of Trileptal:

Trileptal (21,590 reports)

Myelodysplastic syndrome treatments and more:

Myelodysplastic syndrome (49,651 reports)

COVID vaccines that are related to Myelodysplastic syndrome:

How severe was Myelodysplastic syndrome and when was it recovered:

Myelodysplastic syndrome in Trileptal

Expand to all the drugs that have ingredients of oxcarbazepine:

Myelodysplastic syndrome and drugs with ingredients of oxcarbazepine (3 reports)

Common drugs associated with Myelodysplastic syndrome:

All the drugs that are associated with Myelodysplastic syndrome:

Myelodysplastic syndrome (1,255 drugs)

Common conditions associated with Myelodysplastic syndrome:

All the conditions that are associated with Myelodysplastic syndrome:

Myelodysplastic syndrome (957 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxcarbazepine (the active ingredients of Trileptal) and Trileptal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.