Trulicity and Cardiac murmur - a phase IV clinical study of FDA data
Summary:
We study 69,963 people who have side effects when taking Trulicity. Cardiac murmur is found, especially among people who are female, 60+ old, also take Xyrem and have Cataplexy.
The phase IV clinical study analyzes which people take Trulicity and have Cardiac murmur. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
69,963 people reported to have side effects when taking Trulicity.
Among them, 15 people (0.02%) have Cardiac murmur.
What is Trulicity?
Trulicity has active ingredients of dulaglutide. It is used in weight loss. Currently, eHealthMe is studying from 70,509 Trulicity users.
What is Cardiac murmur?
Cardiac murmur (an heart sound in valve abnormality) is found to be associated with 1,976 drugs and 1,127 conditions by eHealthMe. Currently, we are studying 14,203 people who have Cardiac murmur.
Number of Trulicity and Cardiac murmur reports submitted per year:

Gender of people who have Cardiac murmur when taking Trulicity *:
- female: 73.33 %
- male: 26.67 %
Age of people who have Cardiac murmur when taking Trulicity *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 25.0 %
- 50-59: 37.5 %
- 60+: 37.5 %
Common drugs people take besides Trulicity *:
- Xyrem: 5 people, 33.33%
- Abilify: 4 people, 26.67%
- Zanaflex: 4 people, 26.67%
- Provigil: 4 people, 26.67%
- Vitamin D3: 4 people, 26.67%
- Nucynta: 4 people, 26.67%
- Victoza: 4 people, 26.67%
- Lipitor: 4 people, 26.67%
- Jardiance: 3 people, 20.00%
- Percocet: 3 people, 20.00%
Common side effects people have besides Cardiac murmur *:
- Blood Glucose Decreased: 4 people, 26.67%
- Cataract (clouding of the lens inside the eye): 4 people, 26.67%
- Weight Increased: 3 people, 20.00%
- Fatigue (feeling of tiredness): 3 people, 20.00%
- Lacrimation Increased: 3 people, 20.00%
- Insomnia (sleeplessness): 3 people, 20.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 20.00%
- High Blood Pressure: 3 people, 20.00%
- Feeling Abnormal: 3 people, 20.00%
- Dizziness: 3 people, 20.00%
Common conditions people have *:
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 33.33%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 33.33%
- Type 2 Diabetes: 3 people, 20.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 20.00%
- Cushing's Syndrome (obesity, a rounded face, increased fat): 3 people, 20.00%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.67%
- High Blood Pressure: 1 person, 6.67%
- Drowsiness: 1 person, 6.67%
- Depression: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Trulicity and have Cardiac murmur?
Check whether Cardiac murmur is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Trulicity side effects by duration, gender and age:
- Trulicity side effects (70,509 reports)
Cardiac murmur treatments and more:
- Cardiac murmur (14,203 reports)
Common drugs associated with Cardiac murmur:
- Paxil: 2,239 reports
- Fosamax: 1,335 reports
- Aspirin: 1,072 reports
- Furosemide: 908 reports
- Vioxx: 899 reports
- Prednisone: 843 reports
- Zofran: 829 reports
- Lasix: 820 reports
- Digoxin: 766 reports
- Zoloft: 635 reports
All the drugs that are associated with Cardiac murmur:
- Cardiac murmur (1,976 drugs)
Common conditions associated with Cardiac murmur:
- Depression: 1,406 reports
- Osteoporosis: 1,084 reports
- High blood pressure: 789 reports
- Stress and anxiety: 707 reports
All the conditions that are associated with Cardiac murmur:
- Cardiac murmur (1,127 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on dulaglutide (the active ingredients of Trulicity) and Trulicity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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