Trusopt and Arthritis - a phase IV clinical study of FDA data


Arthritis is found among people who take Trusopt, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Trusopt and have Arthritis. It is created by eHealthMe based on reports of 2,956 people who have side effects when taking Trusopt from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 26, 2023

2,956 people reported to have side effects when taking Trusopt.
Among them, 22 people (0.74%) have Arthritis.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 2,998 Trusopt users for its effectiveness, alternative drugs and more.

What is Arthritis?

Arthritis (form of joint disorder that involves inflammation of one or more joints) is found to be associated with 2,939 drugs and 2,230 conditions by eHealthMe.

Number of Trusopt and Arthritis reports submitted per year:

Could Trusopt cause Arthritis?

Time on Trusopt when people have Arthritis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Arthritis when taking Trusopt *:

  • female: 54.55 %
  • male: 45.45 %

Age of people who have Arthritis when taking Trusopt *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 9.09 %
  • 60+: 90.91 %

Common drugs people take besides Trusopt *:

  1. Xalatan: 17 people, 77.27%
  2. Prilosec: 11 people, 50.00%
  3. Lasix: 11 people, 50.00%
  4. Prednisone: 10 people, 45.45%
  5. Elavil: 9 people, 40.91%
  6. Plavix: 9 people, 40.91%
  7. Celebrex: 9 people, 40.91%
  8. Coumadin: 9 people, 40.91%
  9. Magnesium: 9 people, 40.91%
  10. Zometa: 9 people, 40.91%

Common side effects people have besides Arthritis *:

  1. Pain: 15 people, 68.18%
  2. Cataract (clouding of the lens inside the eye): 15 people, 68.18%
  3. Dizziness: 14 people, 63.64%
  4. Tinnitus (a ringing in the ears): 13 people, 59.09%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 50.00%
  6. Joint Pain: 11 people, 50.00%
  7. Ocular Hypertension (intraocular pressure higher than normal): 11 people, 50.00%
  8. Back Pain: 11 people, 50.00%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 10 people, 45.45%
  10. Dyspnea Exertional: 10 people, 45.45%

Common conditions people have *:

  1. Stable Angina (a constant chest pain): 9 people, 40.91%
  2. Multiple Myeloma (cancer of the plasma cells): 9 people, 40.91%
  3. Depression: 9 people, 40.91%
  4. Arrhythmias (irregular heartbeat): 9 people, 40.91%
  5. High Blood Pressure: 7 people, 31.82%
  6. Thyroid Diseases: 6 people, 27.27%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 27.27%
  8. Intraocular Pressure Increased: 5 people, 22.73%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 4.55%
  10. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Trusopt and have Arthritis?

Check whether Arthritis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

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Expand to all the drugs that have ingredients of dorzolamide hydrochloride:

Alternative drugs to, pros and cons of Trusopt:

Common Trusopt side effects:

Browse all side effects of Trusopt:

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Arthritis treatments and more:

COVID vaccines that are related to Arthritis:

Common drugs associated with Arthritis:

All the drugs that are associated with Arthritis:

Common conditions associated with Arthritis:

All the conditions that are associated with Arthritis:

How the study uses the data?

The study uses data from the FDA. It is based on dorzolamide hydrochloride (the active ingredients of Trusopt) and Trusopt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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