Truvada and Gastrointestinal inflammation - a phase IV clinical study of FDA data

• Truvada (51,922 reports)

• Abdominal discomfort: 163 reports
• Abdominal distension: 181 reports
• Abdominal pain: 373 reports
• Abdominal pain upper: 229 reports
• Abnormal dreams: 113 reports
• Abortion induced (medically referred abortion): 315 reports
• Abortion spontaneous (naturally occurring miscarriage): 879 reports
• Acute kidney failure: 8,195 reports
• Agitation (state of anxiety or nervous excitement): 123 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 330 reports
• Alanine aminotransferase increased: 354 reports
• Anaemia (lack of blood): 757 reports
• Anhedonia (inability to experience pleasure from activities usually found enjoyable): 6,613 reports
• Ankle fracture: 391 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 238 reports
• Arrhythmias (irregular heartbeat): 137 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 122 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 8,601 reports
• Aspartate aminotransferase increased: 292 reports
• Back pain: 394 reports
• Birth control: 466 reports
• Blood alkaline phosphatase increased: 171 reports
• Blood bilirubin increased: 211 reports
• Blood creatine phosphokinase increased: 141 reports
• Blood creatinine increased: 1,459 reports
• Blood hiv rna increased: 159 reports
• Bone density decreased: 16,568 reports
• Bone disorder: 337 reports
• Bone loss: 8,267 reports
• Bone pain: 161 reports
• Breathing difficulty: 395 reports
• Broken bone: 3,875 reports
• Cardiac murmur (an heart sound in valve abnormality): 156 reports
• Cd4 lymphocytes decreased: 106 reports
• Chest pain: 202 reports
• Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 210 reports
• Chronic kidney disease: 15,734 reports
• Confusional state: 192 reports
• Congenital anomaly (birth defect): 125 reports
• Constipation: 132 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 139 reports
• Cough: 165 reports
• Cytolytic hepatitis (dissolution or destruction of a liver cell): 142 reports
• Death: 506 reports
• Decreased activity: 280 reports
• Dehydration (dryness resulting from the removal of water): 202 reports
• Dental caries: 151 reports
• Depressed mood: 109 reports
• Depression: 1,268 reports
• Diabetes: 207 reports
• Diarrhea: 1,050 reports
• Dizziness: 532 reports
• Drowsiness: 186 reports
• Drug exposure during pregnancy: 661 reports
• Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications): 111 reports
• Drug ineffective: 573 reports
• Drug resistance (reduction in effectiveness of a drug): 179 reports
• Dyslipidaemia (abnormal amount of lipids): 102 reports
• Emotional distress: 7,742 reports
• Erection problems: 111 reports
• Erythema multiforme (a type of hypersensitivity reaction): 149 reports
• Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it): 130 reports
• Fall: 178 reports
• Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system): 430 reports
• Fatigue (feeling of tiredness): 974 reports
• Fear: 110 reports
• Femur fracture: 149 reports
• Fever: 895 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 1,396 reports
• Foot fracture: 539 reports
• Gait disturbance: 232 reports
• Gallstones (stone formation by bile component): 142 reports
• Gamma-glutamyltransferase increased: 160 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 104 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 114 reports
• General physical health deterioration (weak health status): 203 reports
• Glomerular filtration rate decreased: 197 reports
• Haematuria (presence of blood in urine): 162 reports
• Haemoglobin decreased: 162 reports
• Hand fracture: 255 reports
• Headache (pain in head): 681 reports
• Heart attack: 178 reports
• Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 133 reports
• Hepatic enzyme increased: 217 reports
• Hepatic failure (liver failure): 150 reports
• Hepatitis (inflammation of the liver): 208 reports
• Hepatitis c: 163 reports
• Hepatocellular injury (liver injury): 184 reports
• Hepatotoxicity (chemical-driven liver damage): 156 reports
• High blood cholesterol: 194 reports
• High blood pressure: 340 reports
• Hip fracture: 289 reports
• Hip joint replacement: 374 reports
• Hyperbilirubinaemia (excess of bilirubin in the blood): 230 reports
• Hyperkalemia (damage to or disease of the kidney): 128 reports
• Hypersensitivity: 202 reports
• Hypoaesthesia (reduced sense of touch or sensation): 184 reports
• Hypokalemia (low potassium): 143 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 151 reports
• Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 114 reports
• Hypotension (abnormally low blood pressure): 178 reports
• Immune reconstitution syndrome (immune recovery syndrome): 320 reports
• Impaired work ability: 123 reports
• Injury: 159 reports
• Insomnia (sleeplessness): 416 reports
• Interstitial nephritis (inflammation of the kidney): 134 reports
• Intervertebral disc degeneration (spinal disc degeneration): 204 reports
• Itching: 405 reports
• Jaundice - yellow skin (a yellowish pigmentation of the skin): 333 reports
• Joint pain: 588 reports
• Kidney stones: 491 reports
• Lactic acidosis (low ph in body tissues): 126 reports
• Leukopenia (less number of white blood cells in blood): 127 reports
• Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 232 reports
• Live birth: 165 reports
• Liver disorder (liver diseases): 188 reports
• Loss of consciousness: 113 reports
• Low birth weight baby: 124 reports
• Lower limb fracture: 240 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 153 reports
• Lymphoma (cancer that begins in immune system cells): 117 reports
• Malaise (a feeling of general discomfort or uneasiness): 315 reports
• Maternal drugs affecting foetus (chemical affecting the baby before birth taken by mother): 144 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 742 reports
• Memory loss: 154 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 125 reports
• Mobility decreased (ability to move is reduced): 268 reports
• Multiple fractures: 5,565 reports
• Muscle aches (muscle pain): 267 reports
• Muscle spasms (muscle contraction): 110 reports
• Nausea (feeling of having an urge to vomit): 977 reports
• Nausea and vomiting: 721 reports
• Nephropathy (damage to or disease of a kidney): 1,006 reports
• Neuropathy peripheral (surface nerve damage): 226 reports
• Normal newborn: 142 reports
• Oedema peripheral (superficial swelling): 159 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 522 reports
• Osteomalacia (softening of the bones due to a lack of vitamin d): 329 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 3,153 reports
• Osteoporosis (bones weak and more likely to break): 6,935 reports
• Osteoporotic fracture (fracture due to weak bone): 117 reports
• Overdose: 205 reports
• Pain: 7,967 reports
• Pain in extremity: 340 reports
• Pancreatitis (inflammation of pancreas): 170 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 272 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 187 reports
• Patent ductus arteriosus (condition in which the ductus arteriosus does not close): 123 reports
• Pneumonia: 330 reports
• Premature baby: 570 reports
• Premature delivery: 137 reports
• Premature labor: 162 reports
• Protein - urine: 489 reports
• Pulmonary embolism (blockage of the main artery of the lung): 102 reports
• Quality of life decreased: 429 reports
• Rashes (redness): 914 reports
• Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 139 reports
• Renal colic (renal pain): 129 reports
• Renal cyst (kidney cyst): 125 reports
• Renal disorder (kidney disease): 388 reports
• Renal failure acute (rapid kidney dysfunction): 642 reports
• Renal impairment (severely reduced kidney function): 1,383 reports
• Renal injury (kidney injury): 8,646 reports
• Renal tubular disorder (disease of kidney tubules): 238 reports
• Renal tubular necrosis (death of kidney tubules): 177 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 183 reports
• Rib fracture: 407 reports
• Rickets (softening of bones): 900 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 249 reports
• Sinusitis (inflammation of sinus): 101 reports
• Skeletal injury (bone and supporting muscle injury): 7,757 reports
• Sleep disorder: 125 reports
• Spinal compression fracture (fracture due to spinal compression on bone): 170 reports
• Spinal fracture (fracture in one of vertebrae): 195 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 222 reports
• Stillbirth (a birth of dead foetus): 238 reports
• Stress and anxiety: 7,054 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 104 reports
• Suicidal ideation: 197 reports
• Suicide attempt: 143 reports
• Swallowing difficulty: 192 reports
• Thrombocytopenia (decrease of platelets in blood): 497 reports
• Tooth disorder (tooth disease): 108 reports
• Tooth fracture: 369 reports
• Tooth injury: 2,275 reports
• Tooth loss: 8,227 reports
• Transaminases increased: 121 reports
• Upper limb fracture: 247 reports
• Urinary tract infection: 143 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 112 reports
• Ventricular septal defect (a hole in the heart, is a common heart defect that's present at birth (congenital)): 189 reports
• Viral load increased: 212 reports
• Weakness: 641 reports
• Weight decreased: 438 reports
• Weight increased: 278 reports
• White blood cell count decreased: 129 reports
• Wrist fracture: 267 reports

• Gastrointestinal inflammation (7,706 reports)

• Amlodipine: 113 reports
• Aspirin: 187 reports
• Calcium: 154 reports
• Cyclophosphamide: 139 reports
• Enbrel: 126 reports
• Humira: 2,705 reports
• Ibu: 118 reports
• Ibuprofen: 125 reports
• Imuran: 166 reports
• Metformin: 113 reports
• Methotrexate: 461 reports
• Morphine: 111 reports
• Nexium: 135 reports
• Omeprazole: 285 reports
• Pantoprazole: 207 reports
• Pentasa: 133 reports
• Prednisone: 611 reports
• Remicade: 268 reports
• Synthroid: 127 reports
• Tramadol: 104 reports
• Tylenol: 121 reports
• Vitamin b12: 142 reports
• Vitamin d: 213 reports

All the drugs that are associated with Gastrointestinal inflammation:

• Gastrointestinal inflammation (772 drugs)

• Ankylosing spondylitis: 101 reports
• Blood pressure increased: 331 reports
• Crohn's disease: 2,655 reports
• Crohns disease: 2,655 reports
• Feeling uptight: 108 reports
• Gastroesophageal reflux disease: 144 reports
• Hbp: 350 reports
• High blood cholesterol: 123 reports
• High blood pressure: 350 reports
• Hyperlipidemia: 123 reports
• Hypertension: 350 reports
• Ileitis: 2,655 reports
• Inflammatory bowel disease - crohn's disease: 2,655 reports
• Lipid test: 130 reports
• Lipoprotein test: 123 reports
• Multiple sclerosis: 115 reports
• Pain: 224 reports
• Pain management: 224 reports
• Psoriatic arthropathy aggravated: 126 reports
• Rheumatoid arthritis: 327 reports
• Stress and anxiety: 108 reports
• Uc: 527 reports
• Ulcerative colitis: 527 reports

All the conditions that are associated with Gastrointestinal inflammation:

• Gastrointestinal inflammation (511 conditions)

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