Truvada and Lip swelling - a phase IV clinical study of FDA data


Lip swelling is found among people who take Truvada, especially for people who are female, 30-39 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Truvada and have Lip swelling. It is created by eHealthMe based on reports of 72,390 people who have side effects when taking Truvada from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 18, 2023

72,390 people reported to have side effects when taking Truvada.
Among them, 34 people (0.05%) have Lip swelling.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 73,078 Truvada users for its effectiveness, alternative drugs and more.

What is Lip swelling?

Lip swelling is found to be associated with 2,306 drugs and 1,539 conditions by eHealthMe.

Number of Truvada and Lip swelling reports submitted per year:

Could Truvada cause Lip swelling?

Time on Truvada when people have Lip swelling *:

  • < 1 month: 80 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Lip swelling when taking Truvada *:

  • female: 61.76 %
  • male: 38.24 %

Age of people who have Lip swelling when taking Truvada *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.41 %
  • 30-39: 40.74 %
  • 40-49: 37.04 %
  • 50-59: 14.81 %
  • 60+: 0.0 %

Common drugs people take besides Truvada *:

  1. Norvir: 10 people, 29.41%
  2. Loratadine: 5 people, 14.71%
  3. Darunavir: 5 people, 14.71%
  4. Reyataz: 5 people, 14.71%
  5. Isentress: 4 people, 11.76%
  6. Ritonavir: 4 people, 11.76%
  7. Kaletra: 4 people, 11.76%
  8. Edurant: 3 people, 8.82%
  9. Dexamethasone: 2 people, 5.88%
  10. Lactobacillus Rhamnosus: 2 people, 5.88%

Common side effects people have besides Lip swelling *:

  1. Rashes (redness): 14 people, 41.18%
  2. Hypersensitivity: 7 people, 20.59%
  3. Malaise (a feeling of general discomfort or uneasiness): 6 people, 17.65%
  4. Itching: 5 people, 14.71%
  5. Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 5 people, 14.71%
  6. Swelling Face: 5 people, 14.71%
  7. Swollen Tongue (swelling of tongue): 4 people, 11.76%
  8. Mouth Ulcers: 4 people, 11.76%
  9. Tongue Ulceration (ulcers on tongue): 4 people, 11.76%
  10. Oral Pain: 3 people, 8.82%

Common conditions people have *:

  1. Hiv Test Positive: 3 people, 8.82%
  2. High Blood Pressure: 3 people, 8.82%
  3. Chills (felling of cold): 2 people, 5.88%
  4. Hepatitis C: 2 people, 5.88%
  5. Oedema (fluid collection in tissue): 2 people, 5.88%
  6. Ocular Hyperaemia (an abnormally large amount of blood in eye): 2 people, 5.88%
  7. Nausea (feeling of having an urge to vomit): 2 people, 5.88%
  8. Mouth Ulcers: 2 people, 5.88%
  9. Dyslipidaemia (abnormal amount of lipids): 2 people, 5.88%
  10. Pain: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Truvada and have Lip swelling?

Check whether Lip swelling is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Lip swelling and when was it recovered:

Expand to all the drugs that have ingredients of emtricitabine; tenofovir disoproxil fumarate:

Alternative drugs to, pros and cons of Truvada:

Common Truvada side effects:

Browse all side effects of Truvada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Lip swelling treatments and more:

COVID vaccines that are related to Lip swelling:

Common drugs associated with Lip swelling:

All the drugs that are associated with Lip swelling:

Common conditions associated with Lip swelling:

All the conditions that are associated with Lip swelling:

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Truvada) and Truvada (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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