Tysabri and Gastrointestinal inflammation - a phase IV clinical study of FDA data

• Tysabri (204,993 reports)

• Abasia (inability to walk): 2,080 reports
• Abdominal discomfort: 879 reports
• Abdominal distension: 344 reports
• Abdominal pain: 927 reports
• Abdominal pain upper: 1,534 reports
• Abnormal behavior: 188 reports
• Abnormal dreams: 104 reports
• Abortion spontaneous (naturally occurring miscarriage): 1,462 reports
• Abscess (pus): 120 reports
• Accident: 161 reports
• Acne (skin problems that cause pimples): 189 reports
• Activities of daily living impaired: 115 reports
• Acute kidney failure: 455 reports
• Acute respiratory failure: 125 reports
• Acute upper airway obstruction (blockage occurs in the upper airway): 155 reports
• Adverse drug reaction: 815 reports
• Adverse event: 472 reports
• Adverse reaction: 356 reports
• Affect lability (emotional incontinence): 108 reports
• Aggression: 142 reports
• Agitation (state of anxiety or nervous excitement): 394 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 123 reports
• Agraphia (a loss of the ability to write or to express thoughts in writing because of a brain lesion): 222 reports
• Alanine aminotransferase increased: 336 reports
• Alcoholism (problems with alcohol): 109 reports
• Anaemia (lack of blood): 1,073 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 846 reports
• Anger: 419 reports
• Angioedema (rapid swelling of the dermis): 117 reports
• Ankle fracture: 636 reports
• Ankylosing spondylitis (type of arthritis affecting the spine): 110 reports
• Antibody test positive: 233 reports
• Apathy: 157 reports
• Aphagia (inability or refusal to swallow): 241 reports
• Aphonia (inability to produce voice): 179 reports
• Appendicitis (inflammation of the appendix): 149 reports
• Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts): 108 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 949 reports
• Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 151 reports
• Arrhythmias (irregular heartbeat): 379 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 914 reports
• Arthropathy: 576 reports
• Arthropod bite: 210 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 232 reports
• Aspartate aminotransferase increased: 288 reports
• Asthma: 505 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 327 reports
• Back disorder: 394 reports
• Back injury: 239 reports
• Back pain: 3,620 reports
• Bacterial infection: 167 reports
• Balance disorder: 6,912 reports
• Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 312 reports
• Bedridden: 102 reports
• Bipolar disorder (mood disorder): 251 reports
• Birth control: 516 reports
• Bladder disorder: 632 reports
• Bladder dysfunction: 105 reports
• Blindness: 779 reports
• Blindness transient (sudden loss of vision): 159 reports
• Blindness unilateral: 416 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 220 reports
• Blood alkaline phosphatase increased: 106 reports
• Blood bilirubin increased: 154 reports
• Blood glucose decreased: 188 reports
• Blood glucose increased: 479 reports
• Blood iron decreased: 156 reports
• Blood potassium decreased: 361 reports
• Blood pressure fluctuation: 116 reports
• Blood pressure management: 152 reports
• Blood sodium decreased: 108 reports
• Blood test: 236 reports
• Blood urine present: 196 reports
• Body temperature increased: 299 reports
• Bone disorder: 155 reports
• Bone pain: 443 reports
• Bradycardia (abnormally slow heart action): 131 reports
• Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain): 151 reports
• Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 117 reports
• Breast cancer: 1,161 reports
• Breast cancer female: 149 reports
• Breast lump (localized swelling that feels different from the surrounding breast tissue): 112 reports
• Breathing difficulty: 2,789 reports
• Breathing - slowed or stopped: 143 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1,831 reports
• Burning sensation: 1,149 reports
• Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 152 reports
• Candidiasis (candidiasis or thrush is a fungal infection): 104 reports
• Cardiac arrest: 320 reports
• Cardiac disorder: 480 reports
• Cardiac failure: 129 reports
• Cardiac failure congestive: 323 reports
• Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 200 reports
• Cataract (clouding of the lens inside the eye): 348 reports
• Cellulitis (infection under the skin): 899 reports
• Central nervous system lesion (an abnormality in tissue of brain or spinal cord): 1,926 reports
• Cerebral atrophy (decrement in size of brain): 125 reports
• Cerebral disorder (brain disease): 121 reports
• Cerebral haemorrhage (bleeding within the brain): 167 reports
• Cervical dysplasia (abnormal changes in the cells on the surface of the cervix): 110 reports
• Cervix carcinoma (cancer of cervix): 105 reports
• Chest pain: 2,450 reports
• Chills (felling of cold): 1,415 reports
• Cholecystitis (infection of gallbladder): 110 reports
• Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 148 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 311 reports
• Clostridial infection (infectious conditions by clostridium bacteria): 186 reports
• Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 167 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 4,060 reports
• Colitis (inflammation of colon): 252 reports
• Colon cancer: 229 reports
• Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 891 reports
• Completed suicide (act of taking one's own life): 271 reports
• Concussion (short loss of normal brain function in response to a head injury): 271 reports
• Confusion: 335 reports
• Confusional state: 2,901 reports
• Consciousness - decreased: 299 reports
• Constipation: 1,213 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2,169 reports
• Coronary artery occlusion (complete obstruction of blood flow in a coronary artery): 142 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 174 reports
• Cough: 1,872 reports
• Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 667 reports
• Crying: 483 reports
• Cuts and puncture wounds: 373 reports
• Cyst (a closed sac): 213 reports
• Deafness unilateral: 102 reports
• Death: 2,620 reports
• Decreased immune responsiveness: 607 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 552 reports
• Dehydration (dryness resulting from the removal of water): 1,254 reports
• Delirium (wild excitement): 106 reports
• Dementia (madness): 225 reports
• Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function): 106 reports
• Dental caries: 185 reports
• Depressed level of consciousness: 175 reports
• Depressed mood: 1,073 reports
• Depression: 4,324 reports
• Dermatitis allergic (inflammation of the skin due allergic reaction): 135 reports
• Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens): 192 reports
• Device related infection: 277 reports
• Diabetes: 799 reports
• Diarrhea: 2,854 reports
• Diplopia (double vision): 903 reports
• Discomfort: 202 reports
• Disease progression: 201 reports
• Disturbance in attention: 633 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 230 reports
• Dizziness: 5,827 reports
• Drowsiness: 2,219 reports
• Drug effect decreased: 1,650 reports
• Drug hypersensitivity: 522 reports
• Drug ineffective: 8,217 reports
• Drug intolerance (drug sensitivity): 476 reports
• Drug specific antibody present: 1,239 reports
• Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 151 reports
• Dry eyes (lack of adequate tears): 128 reports
• Dry mouth: 349 reports
• Dry skin: 253 reports
• Dysgraphia (impaired ability to learn to write): 651 reports
• Dyskinesia (abnormality or impairment of voluntary movement): 323 reports
• Dysphemia (stammering or stuttering): 234 reports
• Dysstasia (difficulty in standing): 1,054 reports
• Ear discomfort: 101 reports
• Ear pain: 310 reports
• Eating disorder: 116 reports
• Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 103 reports
• Emotional disorder: 472 reports
• Emotional distress: 563 reports
• Encephalitis (inflammation of the brain): 123 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 135 reports
• Endometrial cancer: 134 reports
• Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 139 reports
• Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 560 reports
• Erection problems: 109 reports
• Escherichia infection (bacterial infection by escherichia coli): 121 reports
• Escherichia urinary tract infection (urinary tract infection by escherichia coli): 205 reports
• Excoriation (to tear or wear off the skin of): 158 reports
• Exostosis (formation of new bone on the surface of a bone): 157 reports
• Eye disorder: 389 reports
• Eye infection: 128 reports
• Eyelid twitch (spontaneous and uncontrolled spasms of the muscles): 168 reports
• Eye movement disorder: 164 reports
• Eye movements - uncontrollable: 105 reports
• Eye pain: 605 reports
• Eye swelling: 209 reports
• Facial pain: 213 reports
• Faecal incontinence (a lack of control over passing stool): 329 reports
• Fainting (loss of consciousness and postural tone): 721 reports
• Fall: 10,212 reports
• Fatigue (feeling of tiredness): 22,672 reports
• Fear: 578 reports
• Feeling cold: 666 reports
• Feeling hot: 1,044 reports
• Femur fracture: 261 reports
• Fever: 3,686 reports
• Fibromyalgia (a long-term condition which causes pain all over the body): 348 reports
• Fibula fracture: 110 reports
• Flatulence (flatus expelled through the anus): 147 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 216 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 419 reports
• Foot fracture: 544 reports
• Frustration (a form of poorly expressed anger): 449 reports
• Fungal infection: 526 reports
• Furuncle (infection of the hair follicle): 103 reports
• Gait disturbance: 11,352 reports
• Gallbladder disorder: 292 reports
• Gallbladder operation: 105 reports
• Gallstones (stone formation by bile component): 461 reports
• Gastric bypass: 101 reports
• Gastric disorder (disease of stomach): 491 reports
• Gastric ulcer (stomach ulcer): 231 reports
• Gastritis (inflammation of stomach): 175 reports
• Gastroenteritis (inflammation of stomach and intestine): 105 reports
• Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 504 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 492 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 668 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 157 reports
• General physical health deterioration (weak health status): 1,377 reports
• General symptom: 2,496 reports
• Glaucoma (increased fluid pressure in the eye with vision loss): 110 reports
• Grand mal convulsion (a type of generalized seizure that affects the entire brain): 207 reports
• Haematochezia (passage of stools containing blood): 136 reports
• Haematocrit decreased: 108 reports
• Haematoma (collection of blood outside the blood vessels): 135 reports
• Haemoglobin decreased: 308 reports
• Haemorrhage (bleeding): 267 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 141 reports
• Hair loss: 1,400 reports
• Hallucinations (sensations that appear real but are created by your mind): 322 reports
• Hand fracture: 141 reports
• Headache (pain in head): 11,560 reports
• Head injury: 2,253 reports
• Hearing impaired: 301 reports
• Hearing loss: 257 reports
• Heart attack: 906 reports
• Heart disease: 101 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 538 reports
• Heart rate decreased: 262 reports
• Heart rate increased: 537 reports
• Heart rate irregular: 134 reports
• Heavy or prolong menstrual bleeding: 196 reports
• Hemiparesis (weakness on one side of the body): 1,069 reports
• Hemiplegia (paralysis of one side of the body): 186 reports
• Hepatic enzyme increased: 812 reports
• Hepatic failure (liver failure): 103 reports
• Hepatic steatosis (fatty liver disease): 120 reports
• Hepatitis (inflammation of the liver): 124 reports
• Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 215 reports
• Herpes virus infection: 110 reports
• Herpes zoster: 2,088 reports
• Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 118 reports
• High blood cholesterol: 416 reports
• High blood pressure: 2,280 reports
• Hip fracture: 649 reports
• Hip joint replacement: 150 reports
• Hoarseness or changing voice: 538 reports
• Hot flush (sudden feelings of heat): 512 reports
• Hyperaesthesia: 149 reports
• Hyperhidrosis (abnormally increased sweating): 617 reports
• Hypersensitivity: 3,507 reports
• Hypoacusis (loss of hearing): 308 reports
• Hypoaesthesia (reduced sense of touch or sensation): 6,336 reports
• Hypoaesthesia facial (reduced sense of touch or sensation on face): 146 reports
• Hypoaesthesia oral (reduced sense of touch or sensation in mouth): 180 reports
• Hypoglycemia (low blood sugar): 119 reports
• Hypokalemia (low potassium): 162 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 101 reports
• Hypophagia (reduced food intake): 176 reports
• Hypotension (abnormally low blood pressure): 1,689 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 190 reports
• Hypotonia (low muscle tone): 187 reports
• Hysterectomy: 328 reports
• Ill-defined disorder: 412 reports
• Immune reconstitution syndrome (immune recovery syndrome): 915 reports
• Immune system disorder: 332 reports
• Immunodeficiency disorders: 105 reports
• Impaired driving ability: 161 reports
• Impaired gastric emptying: 137 reports
• Impaired healing: 322 reports
• Incoherent (talking in a confused and unclear way): 136 reports
• Incontinence (lack of moderation or self-control): 394 reports
• Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 148 reports
• Indigestion: 425 reports
• Infected skin ulcer: 113 reports
• Infection: 1,926 reports
• Inflammation: 238 reports
• Inflammatory bowel disease: 124 reports
• Influenza like illness: 1,689 reports
• Infusion related reaction: 967 reports
• Infusion site bruising: 164 reports
• Infusion site extravasation (flow of (blood or lymph) from infusion site): 176 reports
• Infusion site haematoma (localized swelling filled with blood at infusion site): 213 reports
• Infusion site pain: 360 reports
• Injection site pain: 198 reports
• Injection site reaction: 104 reports
• Injury: 334 reports
• Insomnia (sleeplessness): 2,384 reports
• Intervertebral disc degeneration (spinal disc degeneration): 282 reports
• Intervertebral disc disorder (spinal disc disorder): 149 reports
• Intervertebral disc protrusion (spinal disc protrusion): 849 reports
• Intestinal obstruction: 337 reports
• Irritability: 582 reports
• Irritable bowel syndrome: 205 reports
• Itching: 2,365 reports
• Jc virus test positive: 512 reports
• Joint dislocation (a joint position is changed from normal position): 196 reports
• Joint injury: 439 reports
• Joint pain: 3,936 reports
• Joint stiffness: 263 reports
• Joint swelling: 655 reports
• Kidney infection: 543 reports
• Kidney infection (pyelonephritis): 179 reports
• Kidney stones: 962 reports
• Knee joint replacement: 232 reports
• Laryngitis (inflammation of the larynx): 189 reports
• Leukocytosis (increased white blood cells): 250 reports
• Ligament rupture (tear in ligament): 164 reports
• Ligament sprain (ligament stretched): 245 reports
• Limb discomfort (discomfort in leg): 306 reports
• Limb injury: 376 reports
• Lip swelling: 146 reports
• Liver disorder (liver diseases): 250 reports
• Localised infection (infection at the single location): 289 reports
• Local swelling (swelling at the site of some application of substance or injury): 366 reports
• Loss of consciousness: 1,273 reports
• Loss of control of legs: 1,318 reports
• Low birth weight baby: 139 reports
• Lower limb fracture: 545 reports
• Lower respiratory tract infection: 260 reports
• Lung disorder (lung disease): 285 reports
• Lung infection: 200 reports
• Lung neoplasm malignant (cancer tumour of lung): 201 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 303 reports
• Lymphocyte count increased: 115 reports
• Lymphocytosis (an increase in the number or proportion of lymphocytes in the blood): 113 reports
• Lymphoma (cancer that begins in immune system cells): 123 reports
• Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 144 reports
• Malaise (a feeling of general discomfort or uneasiness): 8,038 reports
• Malignant melanoma (skin cancer rises from melancytes): 420 reports
• Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 114 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 1,791 reports
• Medical device complication: 113 reports
• Memory loss: 10,783 reports
• Meningioma (a diverse set of tumours arising from the meninges): 106 reports
• Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 102 reports
• Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia): 103 reports
• Menstrual disorder (disease of menstrual cycle): 101 reports
• Menstruation irregular: 193 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 574 reports
• Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 1,313 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 318 reports
• Micturition urgency (urgency to pass the urine): 326 reports
• Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night): 109 reports
• Migraine (headache): 2,265 reports
• Mobility decreased (ability to move is reduced): 4,532 reports
• Monoplegia (a paralysis of a single limb): 120 reports
• Mood swings (an extreme or rapid change in mood): 536 reports
• Motor dysfunction (dysfunction of a muscle, nerve, or centre that effects or produces motion): 346 reports
• Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 158 reports
• Movement - uncoordinated: 461 reports
• Multiple allergies (allergy to multiple agents): 479 reports
• Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10,465 reports
• Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 19,931 reports
• Muscle aches (muscle pain): 1,097 reports
• Muscle atrophy (a decrease in the mass of the muscle): 201 reports
• Muscle disorder (muscle disease): 126 reports
• Muscle function loss: 316 reports
• Muscle spasms (muscle contraction): 3,966 reports
• Muscle spasticity (tight or stiff muscles and an inability to control those muscles): 1,680 reports
• Muscle strain (an injury to a muscle in which the muscle fibres tear): 147 reports
• Muscle tightness: 633 reports
• Muscle twitching: 374 reports
• Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 148 reports
• Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 1,988 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 802 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1,865 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 288 reports
• Nasopharyngitis (inflammation of the nasopharynx): 4,880 reports
• Nausea (feeling of having an urge to vomit): 5,279 reports
• Nausea and vomiting: 2,845 reports
• Neck pain: 949 reports
• Neoplasm malignant (cancer tumour): 681 reports
• Nerve compression: 187 reports
• Nerve injury: 165 reports
• Nervousness: 730 reports
• Nervous system disorder (a general class of medical conditions affecting the nervous system): 309 reports
• Neuralgia (pain in one or more nerves): 679 reports
• Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 228 reports
• Neurological symptom (symptoms of nervous system disease): 104 reports
• Neuromyelitis optica (inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis)): 159 reports
• Neuropathy peripheral (surface nerve damage): 468 reports
• Neutralising antibodies positive: 152 reports
• Night sweats (sweating in night): 235 reports
• Nosebleed (bleeding from nose): 174 reports
• Numbness and tingling (unusual prickling sensations): 152 reports
• Ocular hyperaemia (an abnormally large amount of blood in eye): 123 reports
• Oedema (fluid collection in tissue): 152 reports
• Oedema peripheral (superficial swelling): 1,387 reports
• Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight): 631 reports
• Optic neuritis (optic nerve inflammation): 971 reports
• Oral candidiasis (fungal infection of mouth): 114 reports
• Oral herpes (viral infection of mouth): 393 reports
• Oropharyngeal pain: 1,023 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 372 reports
• Osteomyelitis (infection of bone): 327 reports
• Osteoporosis (bones weak and more likely to break): 421 reports
• Otitis (ear infection): 615 reports
• Ovarian cancer (cancer of ovary): 122 reports
• Ovarian cysts (fluid filled sacs of the ovary): 202 reports
• Overdose: 308 reports
• Oxygen saturation decreased: 138 reports
• Pain: 7,416 reports
• Pain in extremity: 6,155 reports
• Pain in jaw: 142 reports
• Paleness (unusual lightness of skin colour): 168 reports
• Pancreatitis (inflammation of pancreas): 274 reports
• Panic disorder: 425 reports
• Panic reaction: 132 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3,151 reports
• Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 120 reports
• Partial seizures (seizures which affect only a part of the brain at onset): 130 reports
• Peripheral coldness: 272 reports
• Peripheral swelling: 463 reports
• Personality change: 167 reports
• Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 119 reports
• Pharyngitis (inflammation of the pharynx, causing a sore throat): 174 reports
• Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 344 reports
• Photophobia (extreme sensitivity to light): 103 reports
• Photosensitivity reaction: 112 reports
• Pleural effusion (water on the lungs): 159 reports
• Pneumonia: 3,532 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 445 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 470 reports
• Poor quality sleep: 274 reports
• Poor venous access: 2,385 reports
• Postoperative wound infection: 130 reports
• Post procedural complication: 320 reports
• Post procedural infection: 192 reports
• Premature baby: 133 reports
• Pressure ulcer: 725 reports
• Presyncope: 117 reports
• Procedural complication: 114 reports
• Procedural pain: 282 reports
• Productive cough: 180 reports
• Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 5,548 reports
• Progressive multiple sclerosis (chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord): 276 reports
• Prostate cancer: 189 reports
• Pruritus allergic (severe allergic itching of the skin): 109 reports
• Pruritus generalised (generalized itching): 292 reports
• Psoriasis (immune-mediated disease that affects the skin): 188 reports
• Psychomotor hyperactivity (feelings of extreme restlessness): 138 reports
• Psychotic disorder: 216 reports
• Pulmonary embolism (blockage of the main artery of the lung): 784 reports
• Pulmonary oedema (fluid accumulation in the lungs): 174 reports
• Pulmonary thrombosis (scarring in the lungs): 143 reports
• Rash erythematous (redness of the skin): 145 reports
• Rashes (redness): 3,389 reports
• Rash macular (small, flat red spots): 183 reports
• Rash papular (redness with papule): 288 reports
• Rash pruritic (redness with itching): 347 reports
• Rectal haemorrhage (bleeding from anus): 113 reports
• Red blood cell count decreased: 128 reports
• Renal cell carcinoma (a kidney cancer): 145 reports
• Renal disorder (kidney disease): 248 reports
• Renal failure acute (rapid kidney dysfunction): 283 reports
• Renal impairment (severely reduced kidney function): 109 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 374 reports
• Respiratory disorder (respiratory disease): 290 reports
• Respiratory tract congestion (blockage on respiratory system): 187 reports
• Respiratory tract infection: 378 reports
• Restless leg syndrome (a powerful urge to move your legs): 196 reports
• Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 197 reports
• Rib fracture: 332 reports
• Rickets (softening of bones): 236 reports
• Road traffic accident: 1,111 reports
• Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 271 reports
• Scar: 147 reports
• Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 207 reports
• Scoliosis (a medical condition in which a person's spine is curved from side to side): 142 reports
• Seasonal allergy (allergic condition due to certain season): 172 reports
• Secondary progressive multiple sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 605 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1,191 reports
• Sensation of heaviness: 670 reports
• Sensory disturbance (sense disturbance): 685 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 1,224 reports
• Septic shock (shock due to blood infection): 226 reports
• Sinus congestion (blockage of sinus): 140 reports
• Sinus disorder (disease of sinus): 297 reports
• Sinus headache (headache caused by sinus infections): 120 reports
• Sinusitis (inflammation of sinus): 2,615 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 1,257 reports
• Skin cancer: 163 reports
• Skin discoloration: 268 reports
• Skin disorder (skin disease): 137 reports
• Skin infection: 155 reports
• Skin ulcer: 176 reports
• Sleep apnea syndrome: 232 reports
• Sleep disorder: 318 reports
• Sluggishness (lacking alertness): 337 reports
• Small for dates baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age): 108 reports
• Small intestinal obstruction (blockage in small intestine): 123 reports
• Sneezing: 160 reports
• Speech disorder: 1,870 reports
• Speech impairment (adult) (inability to speak (adult)): 2,365 reports
• Spinal column stenosis (narrowing of spinal column): 177 reports
• Spinal disorder (disease of spine a back bone): 188 reports
• Spinal fracture (fracture in one of vertebrae): 175 reports
• Spinal fusion surgery: 116 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 122 reports
• Spinal pain (pain in spine): 137 reports
• Sprains (an injury to the ligaments around a joint): 122 reports
• Stable angina (a constant chest pain): 128 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 800 reports
• Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria): 108 reports
• Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 159 reports
• Stomatitis (inflammation of mucous membrane of mouth): 210 reports
• Stress and anxiety: 7,112 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 987 reports
• Suicidal ideation: 546 reports
• Suicide attempt: 354 reports
• Surgery: 737 reports
• Swallowing difficulty: 834 reports
• Swelling: 422 reports
• Swelling face: 343 reports
• Swollen tongue (swelling of tongue): 160 reports
• Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 153 reports
• Taste - impaired: 281 reports
• Temperature intolerance (inability to go in temperature): 975 reports
• Tendonitis (a condition that causes pain and swelling of tendons): 152 reports
• The flu (the flu is caused by an influenza virus): 2,399 reports
• Therapeutic response unexpected: 173 reports
• Thermal burn (burn by heat): 150 reports
• Throat irritation: 259 reports
• Throat tightness: 259 reports
• Thrombocytopenia (decrease of platelets in blood): 490 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 757 reports
• Thyroid cancer: 200 reports
• Thyroid diseases: 246 reports
• Tibia fracture (fracture of lower leg bone): 133 reports
• Tinnitus (a ringing in the ears): 327 reports
• Tooth abscess (pus formation in tooth): 501 reports
• Toothaches (tooth pain): 255 reports
• Tooth disorder (tooth disease): 222 reports
• Tooth extraction: 152 reports
• Tooth fracture: 224 reports
• Tooth loss: 124 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 174 reports
• Traumatic injury of the bladder and urethra: 143 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 3,241 reports
• Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation): 512 reports
• Tumor: 208 reports
• Type 2 diabetes: 149 reports
• Uhthoff's phenomenon (heat intolerance): 217 reports
• Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 187 reports
• Unresponsive to stimuli: 142 reports
• Upper limb fracture: 425 reports
• Upper respiratory tract congestion: 122 reports
• Upper respiratory tract infection: 962 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 1,111 reports
• Urinary retention (the inability to completely or partially empty the bladder): 517 reports
• Urinary tract disorder: 132 reports
• Urinary tract infection: 9,683 reports
• Urination - painful: 550 reports
• Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 499 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 1,939 reports
• Uterine leiomyoma (uterine benign tumour derived from smooth muscle): 244 reports
• Vaginal bleeding: 130 reports
• Vaginal infection: 303 reports
• Vein disorder: 703 reports
• Viith nerve paralysis: 137 reports
• Viral infection: 664 reports
• Vision blurred: 2,118 reports
• Visual acuity reduced (reduced clearness of vision): 826 reports
• Visual field defect: 114 reports
• Visual impairment: 3,319 reports
• Vitamin b12 decreased: 103 reports
• Vitamin d decreased: 344 reports
• Weakness: 14,541 reports
• Weight decreased: 1,967 reports
• Weight increased: 1,411 reports
• Weight loss: 276 reports
• Wheezing (a high-pitched whistling sound made while you breath): 232 reports
• White blood cell count decreased: 474 reports
• White blood cell count increased: 996 reports
• Wound: 281 reports
• Wound infection: 163 reports
• Wrist fracture: 197 reports

• Gastrointestinal inflammation (7,706 reports)

• Amlodipine: 113 reports
• Aspirin: 187 reports
• Calcium: 154 reports
• Cyclophosphamide: 139 reports
• Enbrel: 126 reports
• Humira: 2,705 reports
• Ibu: 118 reports
• Ibuprofen: 125 reports
• Imuran: 166 reports
• Metformin: 113 reports
• Methotrexate: 461 reports
• Morphine: 111 reports
• Nexium: 135 reports
• Omeprazole: 285 reports
• Pantoprazole: 207 reports
• Pentasa: 133 reports
• Prednisone: 611 reports
• Remicade: 268 reports
• Synthroid: 127 reports
• Vitamin b12: 142 reports
• Vitamin d: 213 reports

All the drugs that are associated with Gastrointestinal inflammation:

• Gastrointestinal inflammation (772 drugs)

• Ankylosing spondylitis: 101 reports
• Blood pressure increased: 331 reports
• Crohn's disease: 2,655 reports
• Crohns disease: 2,655 reports
• Feeling uptight: 108 reports
• Gastroesophageal reflux disease: 144 reports
• Hbp: 350 reports
• High blood cholesterol: 123 reports
• High blood pressure: 350 reports
• Hyperlipidemia: 123 reports
• Hypertension: 350 reports
• Ileitis: 2,655 reports
• Inflammatory bowel disease - crohn's disease: 2,655 reports
• Lipid test: 130 reports
• Lipoprotein test: 123 reports
• Multiple sclerosis: 115 reports
• Pain: 224 reports
• Pain management: 224 reports
• Psoriatic arthropathy aggravated: 126 reports
• Rheumatoid arthritis: 327 reports
• Stress and anxiety: 108 reports
• Uc: 527 reports
• Ulcerative colitis: 527 reports

All the conditions that are associated with Gastrointestinal inflammation:

• Gastrointestinal inflammation (511 conditions)

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