Tysabri and Thermohyperaesthesia - a phase IV clinical study of FDA data


Thermohyperaesthesia is reported only by a few people who take Tysabri.

The phase IV clinical study analyzes which people take Tysabri and have Thermohyperaesthesia. It is created by eHealthMe based on reports of 204,501 people who have side effects while taking Tysabri from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 16, 2022

204,501 people reported to have side effects when taking Tysabri.
Among them, 5 people (0.0%) have Thermohyperaesthesia.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 204,990 Tysabri users for its effectiveness, alternative drugs and more.

What is Thermohyperaesthesia?

Thermohyperaesthesia (increased sensibility to heat and cold) is found to be associated with 40 drugs and 28 conditions by eHealthMe.

Number of Tysabri and Thermohyperaesthesia reports submitted per year:

Could Tysabri cause Thermohyperaesthesia?

Gender of people who have Thermohyperaesthesia when taking Tysabri *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Thermohyperaesthesia when taking Tysabri *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 100 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Tysabri *:

  1. Tecfidera: 1 person, 20.00%
  2. Mirena: 1 person, 20.00%

Common side effects people have besides Thermohyperaesthesia *:

  1. Weakness: 3 people, 60.00%
  2. Fatigue (feeling of tiredness): 3 people, 60.00%
  3. Balance Disorder: 2 people, 40.00%
  4. Hypoaesthesia (reduced sense of touch or sensation): 2 people, 40.00%
  5. Memory Loss: 1 person, 20.00%
  6. Laboratory Test Abnormal: 1 person, 20.00%
  7. Jc Virus Test Positive: 1 person, 20.00%
  8. Influenza Like Illness: 1 person, 20.00%
  9. Herpes Virus Infection: 1 person, 20.00%
  10. Gait Disturbance: 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tysabri and have Thermohyperaesthesia?

Check whether Thermohyperaesthesia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Tysabri:

Thermohyperaesthesia treatments and more:

COVID vaccines that are related to Thermohyperaesthesia:

How severe was Thermohyperaesthesia and when was it recovered:

Expand to all the drugs that have ingredients of natalizumab:

All the drugs that are associated with Thermohyperaesthesia:

All the conditions that are associated with Thermohyperaesthesia:

How the study uses the data?

The study uses data from the FDA. It is based on natalizumab (the active ingredients of Tysabri) and Tysabri (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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