Ultram and Discomfort - a phase IV clinical study of FDA data

Summary:

Discomfort is found among people who take Ultram, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Ultram and have Discomfort. It is created by eHealthMe based on reports of 25,693 people who have side effects when taking Ultram from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 29, 2023

25,693 people reported to have side effects when taking Ultram.
Among them, 93 people (0.36%) have Discomfort.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 27,243 Ultram users for its effectiveness, alternative drugs and more.

What is Discomfort?

Discomfort is found to be associated with 2,252 drugs and 1,541 conditions by eHealthMe.

Number of Ultram and Discomfort reports submitted per year:

Time on Ultram when people have Discomfort *:

Gender of people who have Discomfort when taking Ultram *:

female: 81.11 %
male: 18.89 %

Age of people who have Discomfort when taking Ultram *:

Common drugs people take besides Ultram *:

Common side effects people have besides Discomfort *:

Diarrhea: 42 people, 45.16%
Stress And Anxiety: 37 people, 39.78%
Hypotension (abnormally low blood pressure): 32 people, 34.41%
Cough: 30 people, 32.26%
Weakness: 29 people, 31.18%
Hypoaesthesia (reduced sense of touch or sensation): 28 people, 30.11%
Tooth Fracture: 27 people, 29.03%
Back Pain: 26 people, 27.96%
High Blood Pressure: 25 people, 26.88%
Joint Pain: 25 people, 26.88%

Common conditions people have *:

Neoplasm Malignant (cancer tumour): 18 people, 19.35%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 10 people, 10.75%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 9 people, 9.68%
Neuropathy Peripheral (surface nerve damage): 8 people, 8.60%
Osteoporosis (bones weak and more likely to break): 8 people, 8.60%
High Blood Pressure: 6 people, 6.45%
Stress And Anxiety: 6 people, 6.45%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 6.45%
Nausea (feeling of having an urge to vomit): 5 people, 5.38%
Neuralgia (pain in one or more nerves): 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

Do you take Ultram and have Discomfort?

Check whether Discomfort is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .

Related studies

How severe was Discomfort and when was it recovered:

Discomfort in Ultram

Expand to all the drugs that have ingredients of tramadol hydrochloride:

Discomfort and drugs with ingredients of tramadol hydrochloride (675 reports)

Alternative drugs to, pros and cons of Ultram:

Ultram (27,243 reports)

Common Ultram side effects:

Pain: 2,373 reports
Fatigue (feeling of tiredness): 2,096 reports
Weakness: 1,701 reports
Headache (pain in head): 1,674 reports
Stress and anxiety: 1,612 reports
Drug ineffective: 1,603 reports
Dizziness: 1,590 reports

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Discomfort treatments and more:

Discomfort (51,000 reports)

COVID vaccines that are related to Discomfort:

Common drugs associated with Discomfort:

All the drugs that are associated with Discomfort:

Discomfort (2,252 drugs)

Common conditions associated with Discomfort:

Rheumatoid arthritis: 6,376 reports
Birth control: 2,046 reports
High blood pressure: 1,720 reports
Multiple sclerosis: 1,565 reports
Pain: 1,290 reports

All the conditions that are associated with Discomfort:

Discomfort (1,541 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride (the active ingredients of Ultram) and Ultram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.